Takanashi Masato, Asaoka Miho, Imano Masashi, Fujioka Azumi, Oishi Yuka, Matsuda Goro, Chiba Sawako, Hirai Kotaro
Department of Urology National Hospital Organization Yokohama Medical Center Yokohama Kanagawa Japan.
Department of Surgery National Hospital Organization Yokohama Medical Center Yokohama Kanagawa Japan.
IJU Case Rep. 2024 Aug 13;7(5):408-413. doi: 10.1002/iju5.12771. eCollection 2024 Sep.
Primary squamous cell carcinoma of the kidney is rare, with only a few cases reported to date.
A right renal mass was detected in a 73-year-old asymptomatic man. Dynamic contrast-enhanced computed tomography showed a hypodensity mass extending from the upper pole of the kidney to the right lobe of the liver. Renal biopsy revealed that this tumor was squamous cell carcinoma. One month later, computed tomography showed rapid tumor growth. Radical nephrectomy and partial hepatic resection were performed. Pathological analysis indicated that this tumor originated from the tubular epithelium, and the patient was diagnosed with primary squamous cell carcinoma of the kidney.Following up without adjuvant therapy, he developed retroperitoneal recurrence and multiple lung metastases and expired.
In this case, squamous cell carcinoma of the kidney invaded the liver and progressed rapidly. Considering these observations, surgical resection should be promptly performed in suspected cases.
原发性肾鳞状细胞癌罕见，迄今为止仅有少数病例报道。
一名73岁无症状男性被检测出右肾肿物。动态对比增强计算机断层扫描显示一个低密度肿物，从肾上极延伸至肝右叶。肾活检显示该肿瘤为鳞状细胞癌。1个月后，计算机断层扫描显示肿瘤迅速生长。遂行根治性肾切除术和部分肝切除术。病理分析表明该肿瘤起源于肾小管上皮，患者被诊断为原发性肾鳞状细胞癌。未进行辅助治疗进行随访，患者出现腹膜后复发和多发肺转移，最终死亡。
在本病例中，肾鳞状细胞癌侵犯肝脏且进展迅速。基于这些观察结果，对于疑似病例应及时进行手术切除。
