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Expression and Clinical Significance of CREPT and CDK4 in Cervical Cancer.

作者信息

Yao Shenghui, Sun Huili

机构信息

Department of Gynecology, Xuzhou No.1 People's Hospital, Xuzhou 221002, P.R. China.

Department of TCM Physiotherapy, Xuzhou No.1 People's Hospital, Xuzhou 221002, P.R. China.

出版信息

Iran J Public Health. 2021 Feb;50(2):418-420. doi: 10.18502/ijph.v50i2.5365.

DOI:10.18502/ijph.v50i2.5365
PMID:33748010
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7956077/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86ba/7956077/7f89756918b8/IJPH-50-418-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86ba/7956077/7f89756918b8/IJPH-50-418-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86ba/7956077/7f89756918b8/IJPH-50-418-g001.jpg

相似文献

1
Expression and Clinical Significance of CREPT and CDK4 in Cervical Cancer.CREPT和CDK4在宫颈癌中的表达及临床意义
Iran J Public Health. 2021 Feb;50(2):418-420. doi: 10.18502/ijph.v50i2.5365.
2
High expression of CREPT promotes tumor growth and is correlated with poor prognosis in colorectal cancer.CREPT的高表达促进肿瘤生长，且与结直肠癌的不良预后相关。
Biochem Biophys Res Commun. 2016 Nov 18;480(3):436-442. doi: 10.1016/j.bbrc.2016.10.067. Epub 2016 Oct 20.
3
Inhibition of CREPT restrains gastric cancer growth by regulation of cycle arrest, migration and apoptosis via ROS-regulated p53 pathway.CREPT的抑制通过ROS调节的p53途径调控细胞周期阻滞、迁移和凋亡，从而抑制胃癌生长。
Biochem Biophys Res Commun. 2018 Feb 19;496(4):1183-1190. doi: 10.1016/j.bbrc.2018.01.167. Epub 2018 Jan 31.
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CREPT regulated by miR-138 promotes breast cancer progression.受miR-138调控的CREPT促进乳腺癌进展。
Biochem Biophys Res Commun. 2017 Nov 4;493(1):263-269. doi: 10.1016/j.bbrc.2017.09.033. Epub 2017 Sep 8.
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Inhibiting CREPT reduces the proliferation and migration of non-small cell lung cancer cells by down-regulating cell cycle related protein.抑制CREPT可通过下调细胞周期相关蛋白来降低非小细胞肺癌细胞的增殖和迁移。
Am J Transl Res. 2016 May 15;8(5):2097-113. eCollection 2016.
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Expression of CREPT is associated with poor prognosis of patients with renal cell carcinoma.CREPT的表达与肾细胞癌患者的不良预后相关。
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MicroRNA-501-3p restricts prostate cancer growth through regulating cell cycle-related and expression-elevated protein in tumor/cyclin D1 signaling.微小 RNA-501-3p 通过调节肿瘤/周期蛋白 D1 信号通路中的细胞周期相关和表达上调蛋白来限制前列腺癌的生长。
Biochem Biophys Res Commun. 2019 Feb 12;509(3):746-752. doi: 10.1016/j.bbrc.2018.12.176. Epub 2019 Jan 6.
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MicroRNA-449b-5p suppresses the growth and invasion of breast cancer cells via inhibiting CREPT-mediated Wnt/β-catenin signaling.微小 RNA-449b-5p 通过抑制 CREPT 介导的 Wnt/β-连环蛋白信号通路抑制乳腺癌细胞的生长和侵袭。
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CREPT expression correlates with poor prognosis in patients with retroperitoneal leiomyosarcoma.CREPT表达与腹膜后平滑肌肉瘤患者的不良预后相关。
Int J Clin Exp Pathol. 2014 Sep 15;7(10):6596-605. eCollection 2014.
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Cell cycle-related and expression-elevated protein in tumor overexpression is associated with proliferation behaviors and poor prognosis in non-small-cell lung cancer.肿瘤过表达中与细胞周期相关且表达升高的蛋白质与非小细胞肺癌的增殖行为及不良预后相关。
Cancer Sci. 2018 Apr;109(4):1012-1023. doi: 10.1111/cas.13524. Epub 2018 Mar 5.

本文引用的文献

1
Minimally Invasive versus Abdominal Radical Hysterectomy for Cervical Cancer.微创与经腹根治性子宫切除术治疗宫颈癌的比较。
N Engl J Med. 2018 Nov 15;379(20):1895-1904. doi: 10.1056/NEJMoa1806395. Epub 2018 Oct 31.
2
PAQR4 has a tumorigenic effect in human breast cancers in association with reduced CDK4 degradation.PAQR4 在人类乳腺癌中具有致瘤作用，与 CDK4 降解减少有关。
Carcinogenesis. 2018 Mar 8;39(3):439-446. doi: 10.1093/carcin/bgx143.
3
CDK4/6 and autophagy inhibitors synergistically induce senescence in Rb positive cytoplasmic cyclin E negative cancers.
CDK4/6 和自噬抑制剂协同诱导 Rb 阳性细胞质 cyclin E 阴性癌症衰老。
Nat Commun. 2017 Jun 27;8:15916. doi: 10.1038/ncomms15916.
4
Knocking-down of CREPT prohibits the progression of oral squamous cell carcinoma and suppresses cyclin D1 and c-Myc expression.敲低CREPT可抑制口腔鳞状细胞癌的进展，并抑制细胞周期蛋白D1和c-Myc的表达。
PLoS One. 2017 Apr 3;12(4):e0174309. doi: 10.1371/journal.pone.0174309. eCollection 2017.
5
Differences in the outcomes and complications between elderly and younger uterine cervical cancer patients treated by definitive radiotherapy - A propensity score-matched study.根治性放疗治疗老年与年轻子宫颈癌患者的结局和并发症差异——一项倾向评分匹配研究
Gynecol Oncol. 2017 May;145(2):277-283. doi: 10.1016/j.ygyno.2017.02.034. Epub 2017 Mar 6.
6
Palbociclib (PD-0332991), a selective CDK4/6 inhibitor, restricts tumour growth in preclinical models of hepatocellular carcinoma.帕博西尼（PD - 0332991），一种选择性细胞周期蛋白依赖性激酶4/6（CDK4/6）抑制剂，在肝细胞癌的临床前模型中可抑制肿瘤生长。
Gut. 2017 Jul;66(7):1286-1296. doi: 10.1136/gutjnl-2016-312268. Epub 2016 Nov 14.