Balbim Guilherme M, Ajilore Olusola A, Erickson Kirk I, Lamar Melissa, Aguiñaga Susan, Bustamante Eduardo E, Marquez David X
University of Illinois at Chicago, Department of Kinesiology and Nutrition, Chicago, Illinois, United States.
University of Illinois at Chicago, Department of Psychiatry, Chicago, Illinois, United States.
J Cogn Enhanc. 2021 Mar;5(1):1-14. doi: 10.1007/s41465-020-00185-1. Epub 2020 Aug 3.
Dance is a culturally salient form of physical activity (PA) for older Latinos. Resting-state functional connectivity (FC) is a putative biomarker for age-related cognitive decline. We aimed to investigate the impact of the BAILAMOS™ dance program on FC in three brain functional networks (Default Mode [DMN], Frontoparietal [FPN], and Salience [SAL] networks), and cognition. Ten cognitively healthy older Latinos participated in the four-month BAILAMOS™ dance program. We assessed PA levels (self-reported and device-assessed) and estimated cardiorespiratory fitness, cognition, and resting-state FC via functional magnetic resonance imaging at baseline and post-intervention. We performed paired t-tests and Pearson correlations. Given the pilot nature of the study, significance levels were set at < 0.05 and effect sizes are reported. We observed a significant increase in self-reported moderate leisure-time PA from pre- to post-intervention ((9) = 3.16, = 0.011, = 0.66). FC within-FPN regions of interest (ROIs) significantly increased pre- to post-intervention ((9) = 2.35, = 0.043, = 0.70). DMN ROIs showed an increase, with a moderate effect size, in the integration with other networks' ROIs ((9) = 1.96, = 0.081, = 0.64) post-intervention. Increases in moderate leisure-time PA at post-intervention were associated with increases in the FC within-FPN (R = 0.79, = 0.006). Our results suggest that dance might be a promising approach for improving age-related disruption of FC within- and between-networks commonly associated with cognitive decline.
舞蹈是老年拉丁裔群体中一种具有文化特色的体育活动形式。静息态功能连接（FC）被认为是与年龄相关的认知衰退的一种生物标志物。我们旨在研究BAILAMOS™舞蹈项目对三个脑功能网络（默认模式网络[DMN]、额顶叶网络[FPN]和突显网络[SAL]）中的FC以及认知的影响。十名认知健康的老年拉丁裔参与了为期四个月的BAILAMOS™舞蹈项目。我们在基线和干预后通过功能磁共振成像评估了体育活动水平（自我报告和设备评估），并估计了心肺适能、认知和静息态FC。我们进行了配对t检验和Pearson相关性分析。鉴于该研究的探索性性质，显著性水平设定为<0.05，并报告效应量。我们观察到从干预前到干预后，自我报告的中度休闲时间体育活动显著增加（(9)=3.16，=0.011，=0.66）。干预前到干预后，FPN感兴趣区域（ROIs）内的FC显著增加（(9)=2.35，=0.043，=0.70）。干预后，DMN ROIs与其他网络ROIs的整合显示出增加，效应量中等（(9)=1.96，=0.081，=0.64）。干预后中度休闲时间体育活动的增加与FPN内FC的增加相关（R=0.79，=0.006）。我们的结果表明，舞蹈可能是一种有前景的方法，可改善通常与认知衰退相关的网络内和网络间与年龄相关的FC破坏。
