Institute of General and Ecological Chemistry, Faculty of Chemistry, Lodz University of Technology, Lodz, Poland.
Crit Rev Food Sci Nutr. 2022;62(23):6467-6484. doi: 10.1080/10408398.2021.1902261. Epub 2021 Mar 22.
The links between diet and Parkinson's disease (PD) are unclear and incomprehensible. However, numerous studies have demonstrated the correlation between diet, nutrients and health condition in PD patients. They indicate the possibility of management of the disease, which might be possible through nutrition. Pharmaceutical treatment as well as a complementary holistic approach to the patients should be considered. It is of critical importance to understand how the diet and nutrients might influence PD. A better understanding of the relationship between diet and PD could help to better manage the disease explain promising therapeutic approaches, minimize motor and nonmotor symptoms and disease progression based on a personalized diet. In this review, the recent literature on the observed nutrition disorders and the possible role of diet and nutrients in the prevention and potential regression of PD, as well as dietary interventions and supplementation used to manage the disease is revised.
饮食与帕金森病(PD)之间的联系尚不清楚且难以理解。然而,大量研究表明饮食、营养与 PD 患者健康状况之间存在相关性。这些研究提示了通过营养来管理 PD 的可能性,这可能包括药物治疗以及对患者采取补充的整体治疗方法。了解饮食和营养如何影响 PD 非常重要。更好地理解饮食与 PD 之间的关系有助于更好地管理疾病,解释有前途的治疗方法,根据个性化饮食最小化运动和非运动症状以及疾病进展。在这篇综述中,我们回顾了最近关于观察到的营养障碍的文献,以及饮食和营养在 PD 的预防和潜在逆转中的可能作用,以及用于管理疾病的饮食干预和补充。