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帕金森病的营养问题。

Nutritional aspects in Parkinson's disease.

机构信息

Institute of General and Ecological Chemistry, Faculty of Chemistry, Lodz University of Technology, Lodz, Poland.

出版信息

Crit Rev Food Sci Nutr. 2022;62(23):6467-6484. doi: 10.1080/10408398.2021.1902261. Epub 2021 Mar 22.

DOI:10.1080/10408398.2021.1902261
PMID:33749400
Abstract

The links between diet and Parkinson's disease (PD) are unclear and incomprehensible. However, numerous studies have demonstrated the correlation between diet, nutrients and health condition in PD patients. They indicate the possibility of management of the disease, which might be possible through nutrition. Pharmaceutical treatment as well as a complementary holistic approach to the patients should be considered. It is of critical importance to understand how the diet and nutrients might influence PD. A better understanding of the relationship between diet and PD could help to better manage the disease explain promising therapeutic approaches, minimize motor and nonmotor symptoms and disease progression based on a personalized diet. In this review, the recent literature on the observed nutrition disorders and the possible role of diet and nutrients in the prevention and potential regression of PD, as well as dietary interventions and supplementation used to manage the disease is revised.

摘要

饮食与帕金森病(PD)之间的联系尚不清楚且难以理解。然而,大量研究表明饮食、营养与 PD 患者健康状况之间存在相关性。这些研究提示了通过营养来管理 PD 的可能性,这可能包括药物治疗以及对患者采取补充的整体治疗方法。了解饮食和营养如何影响 PD 非常重要。更好地理解饮食与 PD 之间的关系有助于更好地管理疾病,解释有前途的治疗方法,根据个性化饮食最小化运动和非运动症状以及疾病进展。在这篇综述中,我们回顾了最近关于观察到的营养障碍的文献,以及饮食和营养在 PD 的预防和潜在逆转中的可能作用,以及用于管理疾病的饮食干预和补充。

相似文献

1
Nutritional aspects in Parkinson's disease.帕金森病的营养问题。
Crit Rev Food Sci Nutr. 2022;62(23):6467-6484. doi: 10.1080/10408398.2021.1902261. Epub 2021 Mar 22.
2
Nonmotor Parkinson's and Future Directions.非运动型帕金森病及未来发展方向。
Int Rev Neurobiol. 2017;134:1493-1505. doi: 10.1016/bs.irn.2017.05.017. Epub 2017 Jul 4.
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The Role of Diet and Dietary Patterns in Parkinson's Disease.饮食和膳食模式在帕金森病中的作用。
Nutrients. 2022 Oct 25;14(21):4472. doi: 10.3390/nu14214472.
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Wellness, sexual health, and nonmotor Parkinson's.健康、性健康与非运动性帕金森病。
Int Rev Neurobiol. 2022;162:171-184. doi: 10.1016/bs.irn.2021.12.006. Epub 2022 Mar 15.
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Nutrition and Nonmotor Symptoms of Parkinson's Disease.帕金森病的营养与非运动症状
Int Rev Neurobiol. 2017;134:1143-1161. doi: 10.1016/bs.irn.2017.04.013. Epub 2017 Jun 9.
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Personalized Medicine and Nonmotor Symptoms in Parkinson's Disease.帕金森病的个性化医疗与非运动症状
Int Rev Neurobiol. 2017;134:1257-1281. doi: 10.1016/bs.irn.2017.05.015.
7
Does nutritional status affect Parkinson's Disease features and quality of life?营养状况是否会影响帕金森病的特征和生活质量?
PLoS One. 2018 Oct 2;13(10):e0205100. doi: 10.1371/journal.pone.0205100. eCollection 2018.
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The role of one-carbon metabolism and homocysteine in Parkinson's disease onset, pathology and mechanisms.一碳代谢与同型半胱氨酸在帕金森病发病机制、病理中的作用。
Nutr Res Rev. 2019 Dec;32(2):218-230. doi: 10.1017/S0954422419000106. Epub 2019 Jul 15.
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Nonmotor symptoms in Parkinson's disease: expanding the view of Parkinson's disease beyond a pure motor, pure dopaminergic problem.帕金森病的非运动症状:超越单纯的运动、单纯的多巴胺能问题,拓宽对帕金森病的认识。
Neurol Clin. 2013 Aug;31(3 Suppl):S1-16. doi: 10.1016/j.ncl.2013.04.013. Epub 2013 Jun 14.
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Motor, psychiatric and fatigue features associated with nutritional status and its effects on quality of life in Parkinson's disease patients.帕金森病患者中与营养状况相关的运动、精神和疲劳特征及其对生活质量的影响。
PLoS One. 2014 Mar 7;9(3):e91153. doi: 10.1371/journal.pone.0091153. eCollection 2014.

引用本文的文献

1
Effects of dietary supplements, foods, and dietary patterns in Parkinson's disease: meta-analysis and systematic review of randomized and crossover studies.膳食补充剂、食物和饮食模式对帕金森病的影响:随机和交叉研究的荟萃分析和系统评价。
Eur J Clin Nutr. 2024 May;78(5):365-375. doi: 10.1038/s41430-024-01411-1. Epub 2024 Feb 20.
2
Dietary vitamin E intake and risk of Parkinson's disease: a cross-sectional study.膳食维生素E摄入量与帕金森病风险:一项横断面研究。
Front Nutr. 2024 Jan 5;10:1289238. doi: 10.3389/fnut.2023.1289238. eCollection 2023.