Veterinary Clinical Sciences, Washington State University, Pullman, Washington, USA.
Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Canada.
J Vet Emerg Crit Care (San Antonio). 2021 Mar;31(2):167-188. doi: 10.1111/vec.13045. Epub 2021 Mar 10.
To systematically review available evidence to develop guidelines for the prevention of transfusion reactions and monitoring of transfusion administration in dogs and cats.
Evidence evaluation of the literature (identified through Medline searches through Pubmed and Google Scholar searches) was carried out for identified transfusion reaction types in dogs and cats. Evidence was evaluated using PICO (Population, Intervention, Comparison, Outcome) questions generated for each reaction type. Evidence was categorized by level of evidence (LOE) and quality (Good, Fair, or Poor). Guidelines for prevention and monitoring were generated based on the synthesis of the evidence. Consensus on the final recommendations and a proposed transfusion administration monitoring form was achieved through Delphi-style surveys. Draft recommendations and the monitoring form were made available through veterinary specialty listservs and comments were incorporated.
Twenty-nine guidelines and a transfusion administration monitoring form were formulated from the evidence review with a high degree of consensus CONCLUSIONS: This systematic evidence evaluation process yielded recommended prevention and monitoring guidelines and a proposed transfusion administration form. However, significant knowledge gaps were identified, demonstrating the need for additional research in veterinary transfusion medicine.
系统回顾现有证据，为犬猫输血反应预防和输血管理监测制定指南。
对犬猫各输血反应类型进行文献（通过 Medline 在 Pubmed 和 Google Scholar 上进行搜索）评估。使用为每个反应类型生成的 PICO（人群、干预、比较、结局）问题评估证据。根据证据水平（LOE）和质量（好、中、差）对证据进行分类。根据证据综合制定预防和监测指南。通过德尔菲式调查就最终建议和拟议的输血管理监测表达成共识。通过兽医专科名录服务提供建议草案和监测表，并将意见纳入其中。
从证据回顾中制定了 29 条指南和一份输血管理监测表，具有高度共识。
通过系统的证据评估过程，提出了推荐的预防和监测指南以及一份拟议的输血管理表。然而，仍存在显著的知识空白，表明需要在兽医输血医学领域开展更多研究。
