Mannucci Elizabeth, Blong April, Zorn Chelsea, Walton Rebecca
Emergency and Critical Care Department, VCA West Los Angeles Animal Hospital, Los Angeles, CA, United States.
Department of Clinical Sciences, Iowa State University, Ames, IA, United States.
Front Vet Sci. 2023 Feb 7;10:1113846. doi: 10.3389/fvets.2023.1113846. eCollection 2023.
To describe the management of post-operative abdominal hemorrhage with a xenotransfusion of canine lyophilized platelets in a feline patient.
A 9-year-old male castrated domestic shorthair presented for a spontaneous hemoabdomen secondary to hepatic amyloidosis. Clinically significant hemorrhage occurred in the perioperative and post-operative period and the patient received a massive transfusion and anti-fibrinolytic therapy in combination with a xenotransfusion of canine lyophilized platelets at 0.9 × 10 particles/kg and recombinant human factor VIIa (rhFVIIa). The combination of these interventions decreased transfusion requirements in this patient and the xenotransfusion was well tolerated with no acute or immediate transfusion reactions noted.
This case report describes the xenotransfusion of canine lyophilized platelets in a feline patient with severe, non-compressible abdominal hemorrhage.
描述在一只猫科动物患者中使用犬冻干血小板进行异种输血治疗术后腹腔出血的情况。
一只9岁去势家养短毛雄性猫因肝淀粉样变性继发自发性腹腔积血前来就诊。围手术期和术后发生了具有临床意义的出血，该患者接受了大量输血和抗纤溶治疗，并以0.9×10颗粒/千克的剂量进行了犬冻干血小板的异种输血以及重组人凝血因子VIIa（rhFVIIa）治疗。这些干预措施的联合应用减少了该患者的输血需求，且异种输血耐受性良好，未观察到急性或即刻输血反应。
本病例报告描述了在一只患有严重、难以压迫止血的腹腔出血的猫科动物患者中进行犬冻干血小板异种输血的情况。
