1st Department of Pediatrics, Hippokratio General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
University of Nicosia Medical School, Nicosia, Cyprus.
Clin Respir J. 2021 Jul;15(7):794-799. doi: 10.1111/crj.13364. Epub 2021 Mar 28.
The impact on executive function performance of sleep-related disorders in asthmatic children has been scarcely studied in community settings. The aims of the present study were to assess the prevalence of sleep-related breathing disorders (SRBD) in children with intermittent or mild persistent asthma in primary care settings, and to examine the possible correlations with measures of executive function.
We performed a case-control study including 76 children with asthma (intermittent or mild persistent) and 85 healthy controls. The parents of both patients and controls completed the Paediatric Seep Questionnaire (PSQ) and the Behaviour Rating Inventory of Executive Function (BRIEF) questionnaire.
We did not find any statistically significant differences regarding the scales of PSQ. Additionally, there were no statistical differences between asthmatic children and controls regarding the scales of the BRIEF questionnaire. In both asthmatic children and controls the score of the scale of obstructive sleep-related breathing disorder was significantly correlated with the T scores of the two composite scales (BRI and MI) and the Global Executive Composite.
In children with intermittent or mild persistent asthma under the care of private general paediatricians there were no statistically significant differences regarding subjective SBD compared to the healthy controls. Also there were no statistical differences between asthmatic children and controls regarding behavioural correlates of executive function during everyday life.
在社区环境中，睡眠相关障碍对哮喘儿童执行功能表现的影响研究甚少。本研究旨在评估初级保健环境中间歇性或轻度持续性哮喘儿童睡眠相关呼吸障碍（SRBD）的患病率，并探讨其与执行功能测量指标的可能相关性。
我们进行了一项病例对照研究，纳入了 76 例哮喘（间歇性或轻度持续性）患儿和 85 名健康对照者。患儿和对照者的家长均完成了儿童睡眠问卷（PSQ）和行为评定量表修订版（BRIEF）问卷。
我们未发现 PSQ 量表评分存在任何统计学显著差异。此外，哮喘患儿与对照组之间的 BRIEF 问卷各量表评分也无统计学差异。在哮喘患儿和对照组中，阻塞性睡眠相关呼吸障碍量表评分与两个综合量表（BRI 和 MI）和总体执行功能综合量表的 T 评分显著相关。
在接受私人普通儿科医生治疗的间歇性或轻度持续性哮喘患儿中，与健康对照者相比，其主观 SBD 无统计学显著差异。此外，哮喘患儿与对照组之间在日常生活中执行功能的行为相关性方面也无统计学差异。
