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Herlyn-Werner-Wunderlich (HWW) syndrome with kyphoscoliosis: a rare urogenital anomaly in a teenage girl.合并脊柱后凸侧弯的赫林-韦纳-温德利希（HWW）综合征：一名青少年女性罕见的泌尿生殖系统异常。
BMJ Case Rep. 2021 Mar 22;14(3):e238688. doi: 10.1136/bcr-2020-238688.
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Herlyn-Werner-Wunderlich syndrome: clinical considerations and management.赫林-韦纳-温德利希综合征：临床考量与管理
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Herlyn-Werner-Wunderlich syndrome: Report of a delayed diagnosed case with video presentation of the operative technique of vaginal septum resection.赫林-韦纳-温德利希综合征：一例延迟诊断病例报告及阴道纵隔切除术手术技巧的视频展示
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Herlyn-Werner-Wunderlich syndrome: a very rare urogenital anomaly in a teenage girl.赫林-韦纳-温德利希综合征：一名青少年女性中极为罕见的泌尿生殖系统异常。
J Emerg Med. 2015 Mar;48(3):e73-5. doi: 10.1016/j.jemermed.2014.09.064. Epub 2014 Dec 8.
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Late presentation, MR imaging features and surgical treatment of Herlyn-Werner-Wunderlich syndrome (classification 2.2); a case report.赫林-韦纳-温德利希综合征（2.2分类）的延迟表现、磁共振成像特征及外科治疗：病例报告
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Hemivaginal septum resection in a patient with a rare variant of Herlyn-Werner-Wunderlich syndrome.对一名患有罕见变异型赫林-韦纳-温德利希综合征患者进行半阴道隔切除术。
J Minim Invasive Gynecol. 2014 Nov-Dec;21(6):1113-7. doi: 10.1016/j.jmig.2014.05.001. Epub 2014 May 22.

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Kidney Agenesis and Müllerian Duct Anomalies: A Report of Two Cases and Literature Review.肾缺如与苗勒管异常：两例报告及文献复习
Acta Med Litu. 2025;32(1):229-235. doi: 10.15388/Amed.2025.32.1.7. Epub 2025 Feb 18.

本文引用的文献

1
Clinical and radiological findings for early diagnosis of Herlyn-Werner-Wunderlich syndrome in pediatric age: experience of a single center.小儿期赫林-韦纳-温德利希综合征早期诊断的临床及影像学表现：单中心经验
Gynecol Endocrinol. 2018 Jan;34(1):56-58. doi: 10.1080/09513590.2017.1332178. Epub 2017 May 31.
2
The Herlyn-Werner-Wunderlich Syndrome - A Case Report with Radiological Review.赫林-韦纳-温德利希综合征——一例报告及影像学回顾
Pol J Radiol. 2016 Aug 24;81:395-400. doi: 10.12659/PJR.897228. eCollection 2016.
3
Congenital malformations and other comorbidities in 125 women with Mayer-Rokitansky-Küster-Hauser syndrome.125例迈耶-罗基坦斯基-库斯特-豪泽综合征女性患者的先天性畸形及其他合并症
Eur J Obstet Gynecol Reprod Biol. 2016 Dec;207:45-49. doi: 10.1016/j.ejogrb.2016.10.014. Epub 2016 Oct 26.
4
The ESHRE/ESGE consensus on the classification of female genital tract congenital anomalies.ESHRE/ESGE 关于女性生殖道先天性畸形分类的共识。
Hum Reprod. 2013 Aug;28(8):2032-44. doi: 10.1093/humrep/det098. Epub 2013 Jun 14.
5
OHVIRA syndrome (obstructed hemivagina and ipsilateral renal anomaly) with uterus didelphys, an unusual presentation.OHVIRA综合征（梗阻性半阴道和同侧肾异常）合并双子宫，一种不寻常的表现。
J Pediatr Adolesc Gynecol. 2012 Apr;25(2):e23-e25. doi: 10.1016/j.jpag.2011.11.004.
6
Obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome: management and follow-up.梗阻性半阴道与同侧肾异常（OHVIRA）综合征：管理与随访
Fertil Steril. 2007 Apr;87(4):918-22. doi: 10.1016/j.fertnstert.2006.11.015. Epub 2007 Feb 22.
7
Mullerian duct anomalies: imaging and clinical issues.苗勒管异常：影像学与临床问题
Radiology. 2004 Oct;233(1):19-34. doi: 10.1148/radiol.2331020777. Epub 2004 Aug 18.
8
Obstructive Müllerian anomalies: case report, diagnosis, and management.梗阻性苗勒管异常：病例报告、诊断及处理
Am J Obstet Gynecol. 2001 Aug;185(2):338-44. doi: 10.1067/mob.2001.116738.

合并脊柱后凸侧弯的赫林-韦纳-温德利希（HWW）综合征：一名青少年女性罕见的泌尿生殖系统异常。

Herlyn-Werner-Wunderlich (HWW) syndrome with kyphoscoliosis: a rare urogenital anomaly in a teenage girl.

作者信息

Jhirwal Manisha, Singh Pratibha, Sharma Charu, Khera Pushpinder

机构信息

Obstetrics & Gynecology, AIIMS Jodphur, Jodhpur, Rajasthan, India

Obstetrics & Gynecology, AIIMS Jodphur, Jodhpur, Rajasthan, India.

出版信息

BMJ Case Rep. 2021 Mar 22;14(3):e238688. doi: 10.1136/bcr-2020-238688.

DOI:10.1136/bcr-2020-238688
PMID:33753378
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7986945/
Abstract

The obstructed haemivagina with ipsilateral renal agenesis (OHVIRA) syndrome also known as Herlyn-Werner-Wunderlich syndrome, a rare congenital malformation in females, results due to developmental abnormality in the müllerian duct. We are reporting a case of a 14-year-old girl who presented with pain and a lump in abdomen for the last 5 months. The MRI abdomen and pelvis confirmed the diagnosis of OHVIRA syndrome. The patient underwent haematocolpos and haematometra drainage, followed by vaginal septum resection.

摘要

梗阻性半阴道并同侧肾缺如（OHVIRA）综合征，也称为赫林-韦纳-温德利希综合征，是一种罕见的女性先天性畸形，由苗勒管发育异常引起。我们报告一例14岁女孩，在过去5个月中出现腹痛和腹部肿块。腹部和盆腔MRI确诊为OHVIRA综合征。患者接受了阴道积血和子宫积血引流，随后进行了阴道纵隔切除术。