RU Microbiology, Hygiene and Bioactive Molecules, LVMQB/EB, University Hassan II Casablanca, FSTM, P.O. Box 146, 20650, Mohammedia, Morocco.
Department of Biology and Ecology, Faculty of Sciences and Mathematics, University of Nis, 18000, Nis, Serbia.
Arch Microbiol. 2021 Aug;203(6):2887-2894. doi: 10.1007/s00203-021-02288-5. Epub 2021 Mar 22.
The purpose of this work was to assess chemical composition, antibacterial activity against Staphylococcus aureus isolates from catheter-associated infections and antioxidant activity of methanol extracts of three lichens collected from Morocco. The phytochemical analysis of the methanol extracts of these lichens was performed by HPLC-UV method, the predominant phenolic compounds were evernic acid, physodalic acid and usnic acid for Evernia prunastri, Pseudevernia furfuracea and Ramalina farinacea, respectively. Total phenolic compounds and total flavonoid content of all extracts were also determined. As a result, Pseudevernia furfuracea extract had the strongest effect and the highest phenolic compounds content. All extracts showed antibacterial activity against all tested strains (MIC values ranging from 0.078 to 0.625 mg/mL), the strongest inhibition was obtained with the extract of Evernia prunastri.
这项工作的目的是评估三种从摩洛哥采集的地衣的甲醇提取物的化学成分、对导管相关感染金黄色葡萄球菌分离株的抗菌活性和抗氧化活性。通过 HPLC-UV 方法对这些地衣的甲醇提取物进行了植物化学成分分析，结果表明，短叶松萝、碎斑粗皮马勃和长松萝中的主要酚类化合物分别为evernic 酸、physodalic 酸和 usnic 酸。所有提取物的总酚类化合物和总类黄酮含量也进行了测定。结果表明，碎斑粗皮马勃提取物的效果最强，酚类化合物含量最高。所有提取物均显示出对所有测试菌株的抗菌活性（MIC 值范围为 0.078 至 0.625 mg/mL），其中短叶松萝提取物的抑制作用最强。
