Johnson J S, Croall J, Power J S, Armstrong G R
Department of Histopathology, Hope Hospital, Salford, UK.
J Clin Pathol. 1998 Oct;51(10):789-90. doi: 10.1136/jcp.51.10.789.
Serratia marcescens is commonly isolated from the urine of patients with an indwelling urinary catheter and in the absence of symptoms is often regarded as a contaminant. A case of fatal Serratia marcescens septicaemia with meningitis, brain abscesses, and myocarditis discovered at necropsy is described. The patient was an 83 year old man with an indwelling urinary catheter who suffered from several chronic medical conditions and from whose urine Serratia marcescens was isolated at the time of catheterisation. Serratia marcescens can be a virulent pathogen in particular groups of patients and when assessing its significance in catheter urine specimens, consideration should be given to recognised risk factors such as old age, previous antibiotic treatment, and underlying chronic or debilitating disease, even in the absence of clinical symptoms.
粘质沙雷氏菌通常从留置导尿管患者的尿液中分离出来，在没有症状的情况下常被视为污染物。本文描述了一例尸检时发现的致命性粘质沙雷氏菌败血症，伴有脑膜炎、脑脓肿和心肌炎。患者为一名83岁男性，留置导尿管，患有多种慢性疾病，导尿时从其尿液中分离出粘质沙雷氏菌。粘质沙雷氏菌在特定患者群体中可能是一种毒性很强的病原体，在评估其在导尿管尿液标本中的意义时，即使没有临床症状，也应考虑到诸如老年、先前的抗生素治疗以及潜在的慢性或衰弱性疾病等公认的危险因素。
