Emerg Infect Dis. 2021 Apr;27(4):999-1006. doi: 10.3201/eid2704.204078.
Blastomycosis is caused by inhalation of spp. fungi. Limited data are available on the incidence and geographic range of blastomycosis in the United States. To better characterize its epidemiologic features, we analyzed combined surveillance data from the 5 states in which blastomycosis is reportable: Arkansas, Louisiana, Michigan, Minnesota, and Wisconsin. Surveillance identified 4,441 cases during 1987–2018, a mean of 192 cases per year. The mean annual incidence was <1 case/100,000 population in most areas but >20 cases/100,000 population in some northern counties of Wisconsin. Median patient age was 46 years, 2,892 (65%) patients were male, 1,662 (57%) were hospitalized, and 278 (8%) died. The median time from symptom onset to diagnosis was 33 days. The severity of illness and diagnostic delays suggest that surveillance underestimates the true number of cases. More in-depth surveillance in additional states could elucidate blastomycosis incidence and inform efforts to increase awareness.
球孢子菌病是由 spp. 真菌吸入引起的。美国有关球孢子菌病的发病率和地理范围的资料有限。为了更好地描述其流行病学特征，我们分析了美国 5 个报告球孢子菌病的州（阿肯色州、路易斯安那州、密歇根州、明尼苏达州和威斯康星州）的综合监测数据。监测在 1987 年至 2018 年间发现了 4441 例病例，平均每年 192 例。在大多数地区，年平均发病率<1/10 万，但在威斯康星州北部的一些县发病率>20/10 万。中位患者年龄为 46 岁，2892 名（65%）患者为男性，1662 名（57%）住院，278 名（8%）死亡。从症状出现到诊断的中位时间为 33 天。疾病的严重程度和诊断延迟表明监测低估了实际病例数。在更多的州进行更深入的监测可以阐明球孢子菌病的发病率，并为提高认识的努力提供信息。
