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儿童口腔黏膜下纤维化:一种令人担忧的病症及管理挑战。

Oral submucous fibrosis in children: an alarming condition and challenges in management.

作者信息

Rai Anshul, Jain Anuj, Arora Aakash, Motiwale Tejas

机构信息

Dentistry, All India Institute of Medical Science - Bhopal, Bhopal, Madhya Pradesh, India

Department of Trauma and Emergency Medicine, All India Institute of Medical Science - Bhopal, Bhopal, Madhya Pradesh, India.

出版信息

BMJ Case Rep. 2021 Mar 23;14(3):e238718. doi: 10.1136/bcr-2020-238718.

DOI:10.1136/bcr-2020-238718
PMID:33758041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7993289/
Abstract

Oral submucous fibrosis (OSF) is a well-documented potentially malignant condition. It affects most commonly the adult patients of India and Indian subcontinent, only few cases affecting children have been reported in the literature. This paper presents three cases of OSF below the age of 12 years and reviews the aetiology, clinical presentation, treatment modalities in children with improved follow-up results. Clinical features like restricted mouth opening, burning sensation and history of betel nut chewing helps in the diagnosis of the patients, which can be confirmed by histopathological examination. Conservative management and oral physiotherapy in children help in improved mouth opening. Counselling the children, their friends and parents also plays a vital role. The present paper highlights that children on a larger scale are using tobacco products and further studies are required with larger sample size.

摘要

口腔黏膜下纤维化(OSF)是一种有充分文献记载的潜在恶性疾病。它最常影响印度和印度次大陆的成年患者,文献中仅报道了少数几例影响儿童的病例。本文介绍了3例12岁以下的口腔黏膜下纤维化病例,并回顾了其病因、临床表现、治疗方式以及随访结果的改善情况。诸如张口受限、烧灼感和嚼槟榔史等临床特征有助于诊断患者,组织病理学检查可予以确诊。儿童的保守治疗和口腔物理治疗有助于改善张口度。对儿童及其朋友和父母进行咨询也起着至关重要的作用。本文强调,越来越多的儿童在使用烟草制品,需要进行更大样本量的进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fc3/7993289/cbd09adfaa73/bcr-2020-238718f07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fc3/7993289/38adf68e9639/bcr-2020-238718f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fc3/7993289/e7f051da0ad2/bcr-2020-238718f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fc3/7993289/d1dc30f76683/bcr-2020-238718f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fc3/7993289/17d21ee96019/bcr-2020-238718f04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fc3/7993289/b31f56490b0a/bcr-2020-238718f05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fc3/7993289/53036aa9646a/bcr-2020-238718f06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fc3/7993289/cbd09adfaa73/bcr-2020-238718f07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fc3/7993289/38adf68e9639/bcr-2020-238718f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fc3/7993289/e7f051da0ad2/bcr-2020-238718f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fc3/7993289/d1dc30f76683/bcr-2020-238718f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fc3/7993289/17d21ee96019/bcr-2020-238718f04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fc3/7993289/b31f56490b0a/bcr-2020-238718f05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fc3/7993289/53036aa9646a/bcr-2020-238718f06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fc3/7993289/cbd09adfaa73/bcr-2020-238718f07.jpg

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J Maxillofac Oral Surg. 2022 Mar;21(1):290-292. doi: 10.1007/s12663-020-01388-x. Epub 2020 Jul 18.
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Oral submucous fibrosis in a 5 year old child.一名5岁儿童的口腔黏膜下纤维化
Contemp Clin Dent. 2019 Oct-Dec;10(4):679-681. doi: 10.4103/ccd.ccd_898_18.
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Oral submucous fibrosis in children and adolescents: Analysis of 36 cases.儿童和青少年口腔黏膜下纤维化:36例分析
J Indian Soc Pedod Prev Dent. 2020 Apr-Jun;38(2):190-199. doi: 10.4103/JISPPD.JISPPD_173_20.
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J Oral Biol Craniofac Res. 2020 Apr-Jun;10(2):153-157. doi: 10.1016/j.jobcr.2020.03.010. Epub 2020 Apr 10.
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Oral Submucous Fibrosis in Pediatric Patients: A Systematic Review and Protocol for Management.儿童口腔黏膜下纤维化:系统评价与管理方案
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