Murti P R, Bhonsle R B, Pindborg J J, Daftary D K, Gupta P C, Mehta F S
Community Dent Oral Epidemiol. 1985 Dec;13(6):340-1. doi: 10.1111/j.1600-0528.1985.tb00468.x.
Sixty-six patients with oral submucous fibrosis were followed-up for a period of 17 yr (median observation 10 yr) in Ernakulam District, Kerala, India. Oral cancer developed in five (7.6%) patients. The malignant transformation rate in the same sample was 4.5% over a 15-yr observation period (median 8 yr). These findings impart a high degree of malignant potential to this condition.
在印度喀拉拉邦埃尔讷古勒姆区,对66例口腔黏膜下纤维化患者进行了为期17年的随访(中位观察期为10年)。5例(7.6%)患者发生了口腔癌。在15年的观察期内(中位观察期为8年),同一组样本中的恶变率为4.5%。这些发现表明这种疾病具有高度的恶变潜能。