Nucera Eleonora, Urbani Sara, Buonomo Alessandro, De Pasquale Tiziana, Rizzi Angela, Aruanno Arianna, Pucci Stefano
Allergy Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Civitanova Marche Hospital, Civitanova Marche, Italy.
J Asthma Allergy. 2021 Mar 15;14:241-244. doi: 10.2147/JAA.S295748. eCollection 2021.
Gadolinium-based contrast agents (GBCAs) are considered to be safe, although sometimes patients report a hypersensitivity reaction when undergoing magnetic resonance imaging (MRI). The mechanisms of these reactions and of the sensitization to GBCAs are still largely unknown. We describe four cases of patients who experienced immediate adverse reactions to GBCAs with a demonstrated cutaneous hypersensitivity suggesting an IgE-mediated mechanism.
基于钆的造影剂（GBCAs）被认为是安全的，尽管有时患者在接受磁共振成像（MRI）时会报告过敏反应。这些反应以及对GBCAs致敏的机制在很大程度上仍然未知。我们描述了4例对GBCAs发生即刻不良反应的患者，其皮肤过敏反应表明存在IgE介导的机制。
