Department of Plastic Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Department of Ultrasound, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
J Cosmet Dermatol. 2022 Feb;21(2):716-719. doi: 10.1111/jocd.14103. Epub 2021 Mar 29.
Cosmetic injection-induced nodules are tricky to handle in the clinic.
We reported a case of injection-induced nodule receiving the experimental treatment of hyperbaric oxygen therapy (HOT).
A woman presented with multiple red solid nodules on the neck after receiving mesotherapy conducted by syringe. Ultrasound examination showed multiple thickened inflammatory skin tissues on the neck. Pathological biopsy results showed epithelioid granulomas in the dermis, within which there were degenerative necrosis and foreign bodies in the center and multinucleated giant cells around. The bacteria tests remained negative. Diagnosed with foreign body granuloma, the patient rejected the resection or steroids, but willingly took the experimental treatment of HOT instead. After one month, the patient's ultrasound examination showed that the lesion's local hardness got significantly reduced, and the local blood flow increased, indicating the condition improved.
Although the patient's nodule has not been eliminated, some improvements have been achieved. So far there has no case report on HOT treating injection-induced nodules in the literature.
HOT may be considered as a potential alternative when other treatment options cannot be implemented. More research is needed in this field.
美容注射引起的结节在临床上很难处理。
我们报告了一例接受高压氧治疗（HOT）实验治疗的注射引起的结节病例。
一名女性在接受注射器介导的中胚层疗法后，颈部出现多个红色实性结节。超声检查显示颈部多个增厚的炎症性皮肤组织。病理活检结果显示真皮内有上皮样肉芽肿，其中中心有退行性坏死和异物，周围有多核巨细胞。细菌检测结果仍为阴性。诊断为异物肉芽肿，患者拒绝手术切除或使用类固醇，但愿意接受 HOT 的实验治疗。一个月后，患者的超声检查显示病变局部硬度明显降低，局部血流增加，表明病情有所改善。
尽管患者的结节尚未消除，但已取得一些改善。目前文献中尚无关于 HOT 治疗注射引起的结节的病例报告。
当其他治疗方法不可行时，HOT 可能被视为一种潜在的替代选择。该领域需要更多的研究。
