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SARS-CoV-2 存在于 COVID-19 患者的腹腔液中。

SARS-CoV-2 Is Present in Peritoneal Fluid in COVID-19 Patients.

机构信息

General, Emergency and Trauma Surgery dept., Pisa University Hospital, Pisa, Italy.

Virology dept. Pisa University Hospital, Pisa, Italy.

出版信息

Ann Surg. 2020 Sep 1;272(3):e240-e242. doi: 10.1097/SLA.0000000000004030.

Abstract

BACKGROUND

The excretion pathomechanisms of SARS-CoV-2 are actually unknown. No certain data exist about viral load in the different body compartments and fluids during the different disease phases.

MATERIAL AND METHODS

Specific real-time reverse transcriptase-polymerase chain reaction targeting 3 SARS-CoV-e genes were used to detect the presence of the virus.

RESULTS

SARS-CoV-2 was detected in peritoneal fluid at a higher concentration than in respiratory tract.

CONCLUSION

Detection of SARS-CoV-2 in peritoneal fluid has never been reported. The present article represents the very first positive result describing the presence of the virus in peritoneal fluid during an emergency surgical procedure in a COVID-19 sick patient. This article thus represents a warning for increasing the level of awareness and protection for surgeon especially in emergency surgical setting.

摘要

背景

SARS-CoV-2 的排泄发病机制实际上尚不清楚。在不同疾病阶段,不同身体部位和体液中的病毒载量尚无确切数据。

材料和方法

使用针对 3 个 SARS-CoV-e 基因的特定实时逆转录聚合酶链反应来检测病毒的存在。

结果

SARS-CoV-2 在腹腔液中的浓度高于呼吸道。

结论

从未有报道检测到 SARS-CoV-2 在腹腔液中。本文首次描述了 COVID-19 患者急诊手术过程中病毒在腹腔液中的存在,代表了一个警示,需要提高外科医生的意识和保护水平,特别是在急诊手术环境中。

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