Pontifícia Universidade Católica de Campinas, Programa de Pós-Graduação em Ciências da Saúde, Campinas SP, Brazil.
Pontifícia Universidade Católica de Campinas, Faculdade de Medicina, Campinas SP, Brazil.
Arq Neuropsiquiatr. 2021 Feb;79(2):133-138. doi: 10.1590/0004-282X-ANP-2020-0209.
People with epilepsy frequently complain of poor memory.
To assess the occurrence of memory complaints in older adults with epilepsy (OAE) and whether it is associated with clinical variables, objective cognitive performance, and quality of life (QoL).
The Memory Complaint Questionnaire (MAC-Q) was related to objective cognitive performance, the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E), the Quality of Life in Epilepsy Inventory (QOLIE-31), and the clinical characteristics of 83 OAE.
OAE showed worse cognitive performance and higher MAC-Q scores when compared to a similar control group (n=40). Impairment in multiple cognitive domains occurred in 34 (41%) OAE and was associated with older age and lower educational level. Memory complaints (MAC-Q≥25) were reported by 45 (54.2%) OAE and associated with older age, lower educational level, onset at ≥60 years, higher NDDI-E scores, lower QOLIE-31 scores, and impairment in multiple cognitive domains.
OAE presented worse cognitive performance and greater memory complaints. Episode onset at ≥60 years of age was associated with complaints, but not with objective cognitive deficit. We found an association between subjective and objective cognitive performance, with aspects of epilepsy and worse QoL scores.
癫痫患者常抱怨记忆力差。
评估老年癫痫患者（OAE）记忆主诉的发生情况，以及其与临床变量、客观认知表现和生活质量（QoL）的关系。
使用记忆主诉问卷（MAC-Q）与客观认知表现、癫痫神经障碍抑郁量表（NDDI-E）、癫痫生活质量量表（QOLIE-31）以及 83 名 OAE 的临床特征相关联。
与相似的对照组（n=40）相比，OAE 的认知表现更差，MAC-Q 评分更高。34 名（41%）OAE 存在多个认知领域的损害，与年龄较大和教育程度较低有关。45 名（54.2%）OAE 报告有记忆主诉（MAC-Q≥25），与年龄较大、教育程度较低、发病年龄≥60 岁、NDDI-E 评分较高、QOLIE-31 评分较低以及多个认知领域受损有关。
OAE 的认知表现更差，记忆主诉更多。发病年龄≥60 岁与主诉有关，但与客观认知缺陷无关。我们发现主观和客观认知表现与癫痫的某些方面和较差的 QoL 评分之间存在关联。
