Herman Yehonatan, Harel Liora, Nachum Elhanan, Kaplan Eytan, Frenkel George, Tobar Ana, Lowental Alexander, Amarilyo Gil
Day Care Hospitalization Department, Schneider Children's Medical Center of Israel (SCMCI), Petach Tikva, Israel.
Rheumatology Unit, Schneider Children's Medical Center of Israel (SCMCI), Petach Tikva, Israel.
Harefuah. 2021 Feb;160(2):94-97.
Rheumatic fever (RF) is an autoinflammatory disease that is caused by the host response to an infection with group A β-hemolytic streptococcus. In this case report we describe a 15 years old boy with Down syndrome who had unusual presentation of acute rheumatic fever with a fulminant multisystemic which included heart failure secondary to pancarditis and adult respiratory distress syndrome. The final diagnosis was confirmed after cardiac biopsy that was performed during valve replacement surgery and demonstrated Aschoff bodies - a pathognomonic finding in acute rheumatic fever.
风湿热（RF）是一种自身炎症性疾病，由宿主对A组β溶血性链球菌感染的反应引起。在本病例报告中，我们描述了一名患有唐氏综合征的15岁男孩，他以急性风湿热的不寻常表现出现，伴有暴发性多系统症状，包括全心肌炎继发的心力衰竭和成人呼吸窘迫综合征。在瓣膜置换手术期间进行的心脏活检证实了最终诊断，活检显示有阿绍夫小体——急性风湿热的特征性表现。
