Centre for Stress and Age-Related Disease, University of Brighton, Brighton, UK.
The Gender Identity Clinic Tavistock and Portman NHS Foundation Trust, London, UK.
Sports Med. 2021 Jul;51(7):1401-1415. doi: 10.1007/s40279-021-01451-8. Epub 2021 Mar 24.
Sport is historically designated by the binary categorization of male and female that conflicts with modern society. Sport's governing bodies should consider reviewing rules determining the eligibility of athletes in the female category as there may be lasting advantages of previously high testosterone concentrations for transwomen athletes and currently high testosterone concentrations in differences in sex development (DSD) athletes. The use of serum testosterone concentrations to regulate the inclusion of such athletes into the elite female category is currently the objective biomarker that is supported by most available scientific literature, but it has limitations due to the lack of sports performance data before, during or after testosterone suppression. Innovative research studies are needed to identify other biomarkers of testosterone sensitivity/responsiveness, including molecular tools to determine the functional status of androgen receptors. The scientific community also needs to conduct longitudinal studies with specific control groups to generate the biological and sports performance data for individual sports to inform the fair inclusion or exclusion of these athletes. Eligibility of each athlete to a sport-specific policy needs to be based on peer-reviewed scientific evidence made available to policymakers from all scientific communities. However, even the most evidence-based regulations are unlikely to eliminate all differences in performance between cisgender women with and without DSD and transwomen athletes. Any remaining advantage held by transwomen or DSD women could be considered as part of the athlete's unique makeup.
运动在历史上是通过男性和女性的二元分类来指定的,这与现代社会相冲突。体育管理机构应该考虑审查确定女性类别运动员资格的规则,因为对于跨性别女性运动员和目前在性别发育差异(DSD)运动员中高浓度的睾酮可能存在持久的优势。使用血清睾酮浓度来调节此类运动员进入精英女性类别的方法是目前大多数可用科学文献所支持的客观生物标志物,但由于缺乏睾酮抑制之前、期间或之后的运动表现数据,它存在局限性。需要进行创新性的研究来确定其他睾酮敏感性/反应性的生物标志物,包括确定雄激素受体功能状态的分子工具。科学界还需要对特定的对照组进行纵向研究,以生成个体运动的生物学和运动表现数据,为这些运动员的公平参与或排除提供信息。每个运动员对某项特定运动的资格需要基于提供给所有科学界政策制定者的同行评审科学证据。然而,即使是最基于证据的规定也不太可能消除有和没有 DSD 的顺性别女性以及跨性别女性运动员之间的所有表现差异。任何跨性别女性或 DSD 女性保持的优势都可以被视为运动员独特构成的一部分。