Department of Biology, Faculty of Sciences, University of Tehran, Iran.
Medical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences (BUMS), Birjand, Iran; Faculty of Pharmacy, Birjand University of Medical Sciences, Birjand, Iran.
Biomed Pharmacother. 2021 May;137:111374. doi: 10.1016/j.biopha.2021.111374. Epub 2021 Feb 18.
Astaxanthin (ATX) is a red pigment carotenoid present in shrimp, salmon, crab, and asteroidean. Several studies have corroborated the anti-oxidant efficacy of ATX. In addition, ATX has anti-inflammatory, anti-apoptotic and anti-proliferative properties. In the present review, we discuss the role of Nrf2 in mediating the anti-cancer, anti-aging, neuroprotective, lung-protective, skin-protective, cardioprotective, hepatoprotective, anti-diabetic and muscloprotective effects of ATX.
虾青素（ATX）是一种存在于虾、三文鱼、蟹和海星中的红色类胡萝卜素色素。多项研究证实了 ATX 的抗氧化功效。此外，ATX 还具有抗炎、抗细胞凋亡和抗增殖作用。在本综述中，我们讨论了 Nrf2 在介导 ATX 的抗癌、抗衰老、神经保护、肺保护、皮肤保护、心脏保护、肝脏保护、抗糖尿病和肌肉保护作用中的作用。
