体位干预预防妊娠高血压产妇产后下肢深静脉血栓形成的疗效和安全性的系统评价和荟萃分析方案。
Efficacy and safety of postural intervention on prevention of deep venous thrombosis of lower extremity in postpartum women with pregnancy-induced hypertension: A protocol for systematic review and meta-analysis.
机构信息
Department of Interventional Medicine, The First Hospital of Lanzhou University.
Intensive Care Unit, Gansu Provincial Hospital.
出版信息
Medicine (Baltimore). 2021 Mar 26;100(12):e24959. doi: 10.1097/MD.0000000000024959.
BACKGROUND
Deep venous thrombosis (DVT) is a relatively serious complication commonly seen in pregnant women, especially parturients with pregnancy-induced hypertension (PIH), whose incidence of DVT is higher. Because it can lead to pulmonary embolism (PE) and endanger the lives of patients, it has been paid much attention in clinic. Nursing plays an important role in the prevention and treatment of DVT. Early posture intervention can prevent postpartum DVT in hypertensive pregnant women, which has certain clinical value, but there is no evidence of evidence-based medicine. This study aims to systematically study the effectiveness and safety of postural intervention on prevention of deep venous thrombosis of lower extremity in postpartum women with PIH.
METHODS
Use the computer to retrieve the English databases (PubMed, Embase, Web of Science, the Cochrane Library) and the Chinese databases (China Knowledge Network, Wanfang, Weipu, China Biomedical Database), in addition to the manual retrieval of Baidu academic, Google academic, from the construction of database to December 2020, for randomized controlled clinical studies of postural intervention on prevention of deep venous thrombosis of lower extremity in postpartum women with PIH. Two researchers independently extracted the data and evaluated the quality of the included research, and used RevMan5.3 software to do meta-analyze of the included literature.
RESULTS
This study assessed the efficacy and safety of potential intervention on prevention of deep venous thrombosis of lower extremities with lower extremity hypertension by mean velocity of femoral venous flow in the lower extremities, lower extremity skin status, swelling level, and pain condition, lower extremity deep venous thrombosis rate, and incidence of pulmonary embolism.
CONCLUSION
This study will provide reliable evidence-based evidence for the clinical application of postural intervention on prevention of deep venous of lower extremity in Postpartum women with PIH.
OSF REGISTRATION NUMBER
DOI 10.17605/OSF.IO/4NPKW.
背景
深静脉血栓形成（DVT）是孕妇中较为严重的并发症，尤其是妊娠高血压（PIH）产妇，其 DVT 发生率更高。因为它可导致肺栓塞（PE）危及患者生命，故在临床上备受关注。护理在 DVT 的预防和治疗中起着重要作用。早期体位干预可预防高血压孕妇产后 DVT，具有一定的临床价值，但缺乏循证医学证据。本研究旨在系统研究体位干预对预防 PIH 产后下肢深静脉血栓形成的有效性和安全性。
方法
计算机检索英文数据库（PubMed、Embase、Web of Science、The Cochrane Library）和中文数据库（中国知网、万方、维普、中国生物医学文献数据库），并辅以百度学术、Google 学术手工检索，从建库至 2020 年 12 月，收集体位干预预防 PIH 产后下肢深静脉血栓形成的随机对照临床研究。由 2 位研究者独立提取资料并评价纳入研究的质量，采用 RevMan5.3 软件进行 Meta 分析。
结果
本研究通过下肢股静脉血流平均速度、下肢皮肤状况、肿胀程度和疼痛情况、下肢深静脉血栓发生率、肺栓塞发生率评估体位干预对预防下肢高血压产妇下肢深静脉血栓形成的有效性和安全性。
结论
本研究将为体位干预预防 PIH 产后下肢深静脉血栓形成的临床应用提供可靠的循证医学证据。
OSF 注册号：DOI 10.17605/OSF.IO/4NPKW。
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