The Institute of Child Development, University of Minnesota, Minneapolis, MN, USA.
Department of Psychiatry, University of North Carolina at Chapel Hill, NC, USA.
Dev Psychopathol. 2022 Oct;34(4):1447-1467. doi: 10.1017/S0954579420002229. Epub 2021 Mar 25.
Adolescent risk for self-injurious thoughts and behaviors (STBs) involves disturbance across multiple systems (e.g., affective valence, arousal regulatory, cognitive and social processes). However, research integrating information across these systems is lacking. Utilizing a multiple-levels-of-analysis approach, this person-centered study identified psychobiological stress response profiles and linked them to cognitive processes, interpersonal behaviors, and STBs. At baseline, adolescent girls ( = 241, = 14.68 years, 12-17) at risk for STBs completed the Trier Social Stress Test (TSST), questionnaires, and STB interviews. Positive affect (PA), negative affect (NA), and salivary cortisol (SC) were assessed before and after the TSST. STBs were assessed again during 3, 6, and 9 month follow-up interviews. Multitrajectory modeling of girls' PA, NA, and SC revealed four profiles, which were compared on cognitive and behavioral correlates as well as STB outcomes. Relative to , girls in the , , and subgroups were more likely to report negative cognitive style (all three groups) and excessive reassurance seeking ( only) at baseline, as well as nonsuicidal self-injury (all three groups) and suicidal ideation and attempt ( only) at follow-up. Girls' close friendship characteristics moderated several profile-STB links. A synthesis of the findings is presented alongside implications for person-centered tailoring of intervention efforts.
青少年的自伤思想和行为（STBs）风险涉及多个系统（例如，情感效价、唤醒调节、认知和社会过程）的紊乱。然而，缺乏整合这些系统信息的研究。本项以个体为中心的研究利用多层次分析方法，确定了心理生物应激反应特征，并将其与认知过程、人际行为和 STBs 联系起来。在基线时，有 STB 风险的青少年女孩（n = 241，年龄 = 14.68 岁，12-17 岁）完成了特里尔社会应激测试（TSST）、问卷和 STB 访谈。在 TSST 前后评估了积极情绪（PA）、消极情绪（NA）和唾液皮质醇（SC）。在 3、6 和 9 个月的随访访谈中再次评估了 STB。女孩 PA、NA 和 SC 的多轨迹建模揭示了四个特征，这些特征在认知和行为相关性以及 STB 结果方面进行了比较。与 相比，在基线时， 、 和 亚组的女孩更有可能报告消极的认知方式（所有三个组）和过度寻求保证（仅 ），并且在随访时报告非自杀性自伤（所有三个组）和自杀意念和自杀企图（仅 ）。女孩的亲密友谊特征调节了几个特征-STB 联系。本研究提出了一个综合的研究结果，并探讨了针对干预措施的个体为中心的调整的意义。
