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Chronic Dizziness.慢性头晕
Continuum (Minneap Minn). 2021 Apr 1;27(2):420-446. doi: 10.1212/CON.0000000000000932.
3
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Association between dopamine receptor D2 Taq IA gene polymorphism and persistent postural-perceptual dizziness.多巴胺受体 D2 TaqIA 基因多态性与持续性姿势感知性头晕的关系。
J Vestib Res. 2019;29(2-3):131-136. doi: 10.3233/VES-190669.
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Comorbidities, treatment, and pathophysiology in restless legs syndrome.不宁腿综合征的共病、治疗和病理生理学。
Lancet Neurol. 2018 Nov;17(11):994-1005. doi: 10.1016/S1474-4422(18)30311-9. Epub 2018 Sep 21.
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8
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9
Dopa responsive burning mouth syndrome: restless mouth syndrome or oral variant of restless legs syndrome?多巴反应性口面感觉异常症:不安口综合征或不宁腿综合征的口腔变异型?
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10
Restless Legs Syndrome: a common disorder, but rarely diagnosed and barely treated--an Indian experience.不宁腿综合征:一种常见疾病,但很少被诊断和治疗——印度的经验。
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不宁腿综合征患者对左旋多巴或多巴胺激动剂有反应的慢性头晕。

Chronic dizziness in restless legs syndrome (RLS) patients responsive to levodopa or dopamine agonists.

机构信息

Neurolgy, SBKS Medical Institute and Research Centre, Sumandeep Vidyapeeth, Vadodara, India

Neurolgy, SBKS Medical Institute and Research Centre, Sumandeep Vidyapeeth, Vadodara, India.

出版信息

BMJ Case Rep. 2024 Jan 29;17(1):e255700. doi: 10.1136/bcr-2023-255700.

DOI:10.1136/bcr-2023-255700
PMID:38286576
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10826522/
Abstract

Apart from the legs, restless legs syndrome (RLS) also affects the arms, head, neck, face, oral cavity, genital area, abdomen, intestines and bladder. RLS is also linked to several comorbid diseases, including headache disorders. Its association with dizziness has never been explored. We are reporting on two patients with RLS who also had a history of chronic dizziness. The treatment with levodopa or dopamine agonists completely alleviated both RLS and dizziness. We propose that RLS-like symptoms in the head may be experienced as dizziness and that dizziness may be part of the symptom complex of RLS. A large number of patients with chronic dizziness remain undiagnosed in clinical practice. We suggest exploring the history of RLS in patients presenting with chronic dizziness. Such patients may respond to levodopa or dopamine agonists. Because the response was seen in only two patients, a prospective placebo-controlled trial is needed to confirm these findings.

摘要

除了腿部,不宁腿综合征(RLS)还会影响手臂、头部、颈部、面部、口腔、生殖器、腹部、肠道和膀胱。RLS 还与多种合并症相关,包括头痛障碍。其与头晕的关联从未被探讨过。我们报告了两名 RLS 患者,他们也有慢性头晕病史。左旋多巴或多巴胺激动剂治疗完全缓解了 RLS 和头晕。我们提出头部的 RLS 样症状可能被体验为头晕,而头晕可能是 RLS 症状复杂的一部分。在临床实践中,大量慢性头晕患者未被诊断。我们建议在出现慢性头晕的患者中探索 RLS 病史。此类患者可能对左旋多巴或多巴胺激动剂有反应。由于仅在两名患者中观察到这种反应,因此需要进行前瞻性安慰剂对照试验来证实这些发现。