Murthy Ravi, Rachakonda Varun, Bassuner Juri
Departments of Interventional Radiology & Investigational Cancer Therapeutics, M.D. Anderson Cancer Center, The University of Texas at Houston, Houston, Texas 77030, USA.
Houston Methodist Hospital, Department of Radiology, 6565 Fannin St., Houston, TX 77030, USA.
Case Rep Radiol. 2021 Mar 9;2021:6677500. doi: 10.1155/2021/6677500. eCollection 2021.
The development of inoperable biliary obstruction in patients with liver, biliary, and pancreatic neoplasia is commonplace particularly in the advanced stages of these diseases. Under these circumstances, restoring bile flow to the gut is paramount in reestablishing homeostasis. Hitherto, this has been achieved by utilizing passive, gravity-dependent bilioenteric conduits with the use of perforated plastic catheters or metallic stents inserted either in a percutaneous transhepatic fashion or via endoscopic techniques. A frequent untoward event of biliary decompression utilizing percutaneous transhepatic catheters (PTC) is the development of pain, cholangitis, hyperbilirubinemia, or pericatheter bile leak due to the suboptimal normalization of bile flow. In some instances, the etiology of PTC malfunction can be correctly ascribed to catheter malposition and/or catheter lumen obstruction; however, in the majority, it remains radiographically occult on transcatheter cholangiography-the "gold standard." Regardless of findings, the management remains fluoroscopic repositioning or exchanges for larger diameter catheters to attempt to seal the pericatheter potential space and prevent bile seepage. Unfortunately, these maneuvers are met with limited and unpredictable levels of success. We present the successful management of an instance of recalcitrant external pericatheter bile leak mitigated by employing a hybrid closed loop biliary catheter-pump system by employing an assortment of FDA approved off-the-shelf medical devices.
肝、胆和胰腺肿瘤患者出现无法手术的胆道梗阻很常见,尤其是在这些疾病的晚期。在这种情况下,恢复胆汁向肠道的流动对于重建内环境稳定至关重要。迄今为止,这是通过使用被动的、依赖重力的胆肠导管来实现的,即使用经皮经肝方式或通过内镜技术插入的多孔塑料导管或金属支架。使用经皮经肝导管(PTC)进行胆道减压的常见不良事件是由于胆汁流动未达到最佳正常化而出现疼痛、胆管炎、高胆红素血症或导管周围胆汁漏。在某些情况下,PTC故障的病因可正确归因于导管位置不当和/或导管腔阻塞;然而,在大多数情况下,在经导管胆管造影(“金标准”)中,其在影像学上仍不明显。无论检查结果如何,处理方法仍然是在透视下重新定位或更换更大直径的导管,以试图封闭导管周围的潜在间隙并防止胆汁渗漏。不幸的是,这些操作的成功率有限且不可预测。我们介绍了一例顽固性导管周围胆汁漏的成功处理案例,通过使用一种混合闭环胆道导管 - 泵系统,该系统采用了多种经美国食品药品监督管理局(FDA)批准的现成医疗设备。