Department of Dermatology, Kansai Medical University, Osaka, Japan.
J Dermatol. 2021 Jun;48(6):732-740. doi: 10.1111/1346-8138.15840. Epub 2021 Mar 25.
Psoriasis has long been known as a disease with many complications, but was attributed to diet and obesity. However, in recent years, psoriasis itself has been recognized as a series of systemic inflammatory diseases, and that the cytokines involved can induce a variety of other diseases. Individuals with psoriasis were also found to have higher incidences of cerebral and cardiovascular diseases and a younger age at death compared to healthy individuals. However, no clear guidelines have been defined regarding how much vascular lesion testing should be performed in patients with psoriasis. In this report, I attempt to unravel the objective data on psoriasis and its complications from various reviews and reports, and introduce the impact of biologics, which are currently the main treatment for psoriasis, on cardiac vascular disease.
银屑病长期以来一直被认为是一种并发症多的疾病，但归因于饮食和肥胖。然而，近年来，银屑病本身已被确认为一系列系统性炎症性疾病，涉及的细胞因子可诱发多种其他疾病。与健康个体相比，银屑病患者还发现患有脑和心血管疾病的发病率更高，且死亡年龄更小。然而，对于银屑病患者应进行多少血管病变检查，目前尚未制定明确的指南。在本报告中，我尝试从各种综述和报告中梳理出有关银屑病及其并发症的客观数据，并介绍生物制剂的影响，生物制剂目前是银屑病的主要治疗方法，对心血管疾病的影响。
