Eaker E D, Thom T, Castelli W P
National Heart, Lung, and Blood Institute, Epidemiology and Biometry Program, Bethesda, Maryland 20892.
Soz Praventivmed. 1988;33(1):10-6. doi: 10.1007/BF02083999.
The results presented above indicate that the risk factors associated with the development of coronary heart disease in women are not that different than those identified for men. It is encouraging to note that while the prevalence of hypertension in women has not changed over the past twenty years, the proportion of treated hypertensive women has increased dramatically and the proportion with controlled blood pressure has doubled since 1960. It is also encouraging to note that the number of adult women who smoke cigarettes has decreased since 1960, but the number of young girls who smoke has increased at an alarming rate. It has been noted by researchers that among women who smoke, the number of cigarettes smoked per day has increased from the 1950s to the present. From the Framingham data it can be seen that womens' serum cholesterol level increases substantially with age and women should take steps to eat a healthy low-saturated fat, low cholesterol diet in order to maintain a low blood cholesterol level. It has been shown from the Framingham Study data that although the same risk factors operate in men and women, the standard risk factors do not explain the marked differences in morbidity and mortality from heart disease between the two sexes. We must continue to study the epidemiology and biology of coronary heart disease in women both to better understand the disease process in women and to understand the large sex differential for CHD in most westernized countries.
上述结果表明,与女性冠心病发生相关的危险因素与男性所确定的危险因素并无太大差异。值得欣慰的是,尽管过去二十年来女性高血压患病率未变,但接受治疗的高血压女性比例大幅增加,且自1960年以来血压得到控制的女性比例翻了一番。同样值得欣慰的是,自1960年以来,成年吸烟女性人数有所减少,但吸烟少女的数量却以惊人的速度增加。研究人员指出,在吸烟女性中,自20世纪50年代至今,日均吸烟量有所增加。从弗明汉的数据可以看出,女性的血清胆固醇水平随年龄大幅上升,女性应采取措施食用健康的低饱和脂肪、低胆固醇饮食,以维持较低的血液胆固醇水平。弗明汉研究数据表明,尽管男性和女性存在相同的危险因素,但标准危险因素并不能解释两性在心脏病发病率和死亡率方面的显著差异。我们必须继续研究女性冠心病的流行病学和生物学,以便更好地了解女性的疾病进程,并了解大多数西方国家冠心病存在的巨大性别差异。