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采用微创清创术治疗的脊柱感染的预后:两个三级中心的病例系列研究

Prognosis of spinal infections managed by minimal debridement: A case series in two tertiary centers.

作者信息

Mohamed Ahmed Ali, Soffar Hussein Mohammed, El Zayat Hazem Hassan, Aboul-Ela Hashem Mohamed

机构信息

Department of Neurosurgery, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt.

Department of Neurosurgery, Kasr Alainy Faculty of Medicine, Cairo University, Cairo, Egypt.

出版信息

Surg Neurol Int. 2021 Mar 2;12:83. doi: 10.25259/SNI_29_2021. eCollection 2021.

Abstract

BACKGROUND

Spinal infections can be challenging in their management and include spondylitis, epidural abscess, and spondylodiscitis. Usual treatment is conservative through antimicrobials or surgery to decompress neural tissue, debride all infected tissues, and fix if needed. We propose the concept of surgery without formal debridement aiming at neural protection.

METHODS

The study was performed at two tertiary centers on 25 patients with clinical findings. One patient was treated conservatively and the rest surgically by laminectomy and fixation if needed. Evacuation of fluid pus was performed. In the cervical and the thoracic region, if the granulation tissue was anterior to the cord, only decompression by laminectomy was done.

RESULTS

Low back pain was present in 22 cases (88%), 16 cases (64%) had lower limb pain, and 12 cases (48%) had weakness. The level of spinal infection was lumbar in 15 cases (60%), thoracic in 9 cases (36%) cases, and cervical in 1 case (4%). The type of infection was epidural abscess in 20 cases (80%), discitis in 16 cases (64%), and vertebral osteomyelitis in 12 cases (48%). Laminectomy was performed in 20 cases (80%) and fixation in 17 cases (68%). The symptoms improved in all cases. On follow-up, the lesion was reduced in 14 patients (56%) and disappeared in 11 cases (44%). One case required ventriculoperitoneal shunt placement due to postinfectious hydrocephalus.

CONCLUSION

Dealing with spinal infections surgically through decompression or fixation with minimal debridement of infected tissue appears to be a safe and effective method of management.

摘要

背景

脊柱感染的治疗颇具挑战性,包括脊柱炎、硬膜外脓肿和椎间盘炎。通常的治疗方法是通过使用抗菌药物进行保守治疗,或进行手术以减压神经组织、清除所有感染组织,并在必要时进行固定。我们提出了旨在保护神经的无正式清创手术的概念。

方法

该研究在两个三级中心对25例有临床表现的患者进行。1例患者接受保守治疗,其余患者根据需要行椎板切除术和固定术进行手术治疗。进行了脓性液体引流。在颈椎和胸椎区域,如果肉芽组织位于脊髓前方,则仅行椎板切除术减压。

结果

22例(88%)出现腰痛,16例(64%)有下肢疼痛,12例(48%)有肌无力。脊柱感染部位为腰椎15例(60%),胸椎9例(36%),颈椎1例(4%)。感染类型为硬膜外脓肿20例(80%),椎间盘炎16例(64%),椎体骨髓炎12例(48%)。20例(80%)行椎板切除术,17例(68%)行固定术。所有病例症状均有改善。随访时,14例(56%)病变缩小,11例(44%)病变消失。1例因感染后脑积水需要行脑室腹腔分流术。

结论

通过减压或固定、对感染组织进行最小限度清创的手术方式处理脊柱感染似乎是一种安全有效的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2deb/7982097/e193beef6161/SNI-12-83-g001.jpg

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