Lin Mung Yan, Wang Qun, Newman Nancy J, Dattilo Michael
Department of Ophthalmology, Emory Eye Center, Emory University School of Medicine, Atlanta, GA, USA.
Department of Pathology, Emory University School of Medicine, Atlanta, GA, USA.
Taiwan J Ophthalmol. 2021 Jan 25;11(1):104-107. doi: 10.4103/tjo.tjo_84_20. eCollection 2021 Jan-Mar.
Neurosarcoidosis is a rare complication of sarcoidosis and typically presents as acute cranial neuropathies. Neurosarcoidosis can rarely cause an inflammatory optic neuropathy, resembles an optic neuritis and even more rarely can cause an optic perineuritis. Although concomitant optic neuritis and optic perineuritis have been reported in other inflammatory conditions, such as myelin oligodendrocyte antibody-associated disease, spatially-distinct optic neuritis, and optic perineuritis has not been previously described in neurosarcoidosis. Here, we present a case of spatially-distinct concomitant optic neuritis and optic perineuritis from neurosarcoidosis in a 51-year-old man initially suspected to harbor metastatic disease based on imaging findings.
神经结节病是结节病的一种罕见并发症，通常表现为急性颅神经病变。神经结节病极少会引发炎性视神经病变，类似视神经炎，甚至更罕见的情况下会导致视神经周围炎。尽管在其他炎性疾病中，如髓鞘少突胶质细胞抗体相关疾病，曾有视神经炎和视神经周围炎同时出现的报道，但在神经结节病中此前尚未描述过空间上不同部位的视神经炎和视神经周围炎同时存在的情况。在此，我们报告一例51岁男性患者，基于影像学检查结果最初怀疑患有转移性疾病，却发现其患有神经结节病且同时出现了空间上不同部位的视神经炎和视神经周围炎。
