结节病与淋巴瘤？
Sarcoidosis Versus Lymphoma?
作者信息
Dal Lago Lissandra, Sarrand Julie, Woff Erwin, Awada Ahmad, Vouche Michaël, Pepersack Thierry
机构信息
Medical Oncology Department, Institut Jules Bordet - Université Libre de Bruxelles (ULB), Brussels, Belgium.
Nuclear Medicine Department, Institut Jules Bordet - Université Libre de Bruxelles (ULB), Brussels, Belgium.
出版信息
Eur J Case Rep Intern Med. 2021 Feb 15;8(3):002250. doi: 10.12890/2021_002250. eCollection 2021.
UNLABELLED
An association between lymphoma and sarcoidosis was first suggested in 1960. We report a case of sarcoidosis-lymphoma syndrome, which is a diagnostically challenging condition. We conclude that an associated lymphoma should be considered in all patients with suspected sarcoidosis, especially those who do not respond to treatment or who present with persistent haematological abnormalities. Splenomegaly should prompt splenectomy to rule out lymphoma if a less invasive approach has failed to confirm the diagnosis.
LEARNING POINTS
Clinical consideration should be given to an associated lymphoma in all patients with sarcoidosis, especially those who do not respond to treatment or who present with persistent haematological abnormalities.Splenomegaly should raise the possibility of splenectomy to rule out associated lymphoma.
未标注
1960年首次提出淋巴瘤与结节病之间存在关联。我们报告了一例结节病-淋巴瘤综合征病例，这是一种诊断具有挑战性的病症。我们得出结论，所有疑似结节病的患者，尤其是那些对治疗无反应或存在持续性血液学异常的患者，都应考虑是否合并淋巴瘤。如果采用侵入性较小的方法未能确诊，脾肿大应促使进行脾切除术以排除淋巴瘤。
学习要点
所有结节病患者，尤其是那些对治疗无反应或存在持续性血液学异常的患者，都应临床考虑是否合并淋巴瘤。脾肿大应增加进行脾切除术以排除相关淋巴瘤的可能性。
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