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皮肤鳞状细胞癌经抗坏血酸溶液局部治疗后完全缓解：一例报告

Complete response of cutaneous SCC to topical treatment with ascorbic acid solution: A case report.

作者信息

Pernice Carmine, Murri Domenico, Valli Riccardo, Crocetta Francesco M, Iori Michele, Asti Mattia, Ghidini Angelo, Capponi Pier C

机构信息

Otolaryngology Unit Department of Surgery Azienda Unità Sanitaria Locale IRCCS di Reggio Emilia Reggio Emilia Italy.

Pathology Unit Azienda Unità Sanitaria Locale IRCCS di Reggio Emilia Reggio Emilia Italy.

出版信息

Clin Case Rep. 2021 Jan 9;9(3):1060-1065. doi: 10.1002/ccr3.3585. eCollection 2021 Mar.

DOI:10.1002/ccr3.3585
PMID:33768783
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7981708/
Abstract

Clinical use of topical ascorbic acid solution could have both the role as an adjunct to consolidated therapies and as an alternative to them, for the treatment of BCC and SCC of the skin.

摘要

局部应用抗坏血酸溶液在临床上可作为巩固治疗的辅助手段，也可作为其替代方法，用于治疗皮肤基底细胞癌和鳞状细胞癌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7263/7981708/ef7b2e9ab98a/CCR3-9-1060-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7263/7981708/a9ddecae56d3/CCR3-9-1060-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7263/7981708/b61fa0ca7af4/CCR3-9-1060-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7263/7981708/94a8fa1dc5b3/CCR3-9-1060-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7263/7981708/a807e44b9ab2/CCR3-9-1060-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7263/7981708/ef495fc114d0/CCR3-9-1060-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7263/7981708/7eed040d4dec/CCR3-9-1060-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7263/7981708/6a5cd1eab3b7/CCR3-9-1060-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7263/7981708/ae8072ede76f/CCR3-9-1060-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7263/7981708/cc01d0a6fa76/CCR3-9-1060-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7263/7981708/ef7b2e9ab98a/CCR3-9-1060-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7263/7981708/a9ddecae56d3/CCR3-9-1060-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7263/7981708/b61fa0ca7af4/CCR3-9-1060-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7263/7981708/94a8fa1dc5b3/CCR3-9-1060-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7263/7981708/a807e44b9ab2/CCR3-9-1060-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7263/7981708/ef495fc114d0/CCR3-9-1060-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7263/7981708/7eed040d4dec/CCR3-9-1060-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7263/7981708/6a5cd1eab3b7/CCR3-9-1060-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7263/7981708/ae8072ede76f/CCR3-9-1060-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7263/7981708/cc01d0a6fa76/CCR3-9-1060-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7263/7981708/ef7b2e9ab98a/CCR3-9-1060-g005.jpg

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本文引用的文献

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Epidemiology of Skin Cancer: Update 2019.皮肤癌的流行病学：2019 年更新。
Adv Exp Med Biol. 2020;1268:123-139. doi: 10.1007/978-3-030-46227-7_6.
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Clin Drug Investig. 2018 Oct;38(10):883-899. doi: 10.1007/s40261-018-0681-x.
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Actinic keratosis - review for clinical practice.光化性角化病——临床实践综述。
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Pharmaceutics. 2021 Aug 4;13(8):1201. doi: 10.3390/pharmaceutics13081201.
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Tetrahexyldecyl Ascorbate (THDC) Degrades Rapidly under Oxidative Stress but Can Be Stabilized by Acetyl Zingerone to Enhance Collagen Production and Antioxidant Effects.四己基癸醇抗坏血酸酯（THDC）在氧化应激下迅速降解，但可通过乙酰基姜酮稳定化，以增强胶原蛋白生成和抗氧化作用。
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Topically applied ascorbic acid solution for the treatment of basal cell carcinoma (BCC).局部应用抗坏血酸溶液治疗基底细胞癌（BCC）。
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