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Toxicity of tapentadol: a systematic review.曲马多的毒性：一项系统评价。
Pain Manag. 2018 Sep 1;8(5):327-339. doi: 10.2217/pmt-2018-0027. Epub 2018 Aug 6.
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Review of Post-Marketing Safety Data on Tapentadol, a Centrally Acting Analgesic.曲马多（一种中枢作用镇痛药）上市后安全性数据综述。
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Combination treatment of neuropathic pain: Danish expert recommendations based on a Delphi process.神经性疼痛的联合治疗：基于德尔菲法的丹麦专家建议
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Perioperative pregabalin administration does not prevent chronic postoperative pain: systematic review with a meta-analysis of randomized trials.围手术期使用普瑞巴林不能预防慢性术后疼痛：随机试验的系统评价与荟萃分析
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疑似普瑞巴林和曲马多导致的长期脑病及相关非惊厥性癫痫发作：两例病例报告及文献综述

Prolonged encephalopathy and associated nonconvulsive seizures from suspected pregabalin and tapentadol: Two case reports and review of literature.

作者信息

Haji Kavi, Muthu Sachin, Banakh Iouri, Tiruvoipati Ravindranath

机构信息

Department of Intensive Care Medicine Frankston Hospital Frankston Vic. Australia.

School of Public Health Faculty of Medicine, Nursing and Health Sciences Monash University Melbourne Vic. Australia.

出版信息

Clin Case Rep. 2021 Feb 4;9(3):1362-1366. doi: 10.1002/ccr3.3772. eCollection 2021 Mar.

DOI:10.1002/ccr3.3772
PMID:33768845
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7981720/
Abstract

A combination of pregabalin and tapentadol may be associated with prolonged encephalopathy.

摘要

普瑞巴林与曲马多的联合使用可能与延长性脑病有关。