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新型冠状病毒肺炎：一名艾滋病患者的病毒长期脱落情况及关于病毒长期脱落危险因素及其对隔离策略影响的文献综述

COVID-19: Prolonged viral shedding in an HIV patient with literature review of risk factors for prolonged viral shedding and its implications for isolation strategies.

作者信息

Yousaf Muhammad, Hameed Mansoor, Alsoub Hussam, Khatib Mohamad, Jamal Wasim, Ahmad Mushtaq

机构信息

Hazm Mebaireek Hospital Hamad Medical Corporation Doha Qatar.

Weill Cornell Medicine-Qatar Cornell University Doha Qatar.

出版信息

Clin Case Rep. 2021 Jan 13;9(3):1397-1401. doi: 10.1002/ccr3.3786. eCollection 2021 Mar.

DOI:10.1002/ccr3.3786
PMID:33768853
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7981612/
Abstract

Our work highlights patients at risk of prolonged viral shedding in COVID-19 and its implications for isolation strategies and explores possible solution by PCR-CT value testing (cycle threshold value). We also review the impact of HIV on COVID-19.

摘要

我们的研究突出了新冠病毒感染中存在病毒长时间脱落风险的患者及其对隔离策略的影响，并通过聚合酶链式反应-循环阈值检测（CT值检测）探索了可能的解决方案。我们还综述了艾滋病毒对新冠病毒感染的影响。

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COVID-19 in Immunocompromised Hosts: What We Know So Far.免疫功能低下宿主中的 COVID-19：目前我们已知的情况。
Clin Infect Dis. 2021 Jan 27;72(2):340-350. doi: 10.1093/cid/ciaa863.
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Clinical predictors and timing of cessation of viral RNA shedding in patients with COVID-19.新型冠状病毒肺炎患者病毒 RNA 脱落停止的临床预测指标和时间。
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HIV/SARS-CoV-2 coinfection: A global perspective.HIV/SARS-CoV-2 合并感染：全球视角。
可溶性野生型 ACE2 分子可抑制新型 SARS-CoV-2 变体，是减轻 COVID-19 疾病严重程度的一种潜在抗病毒策略。
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Duration of SARS-CoV-2 RNA Shedding Is Significantly Influenced by Disease Severity, Bilateral Pulmonary Infiltrates, Antibiotic Treatment, and Diabetic Status: Consideration for Isolation Period.新型冠状病毒（SARS-CoV-2）RNA脱落持续时间受疾病严重程度、双侧肺部浸润、抗生素治疗及糖尿病状态的显著影响：隔离期的考量因素
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The severity of COVID-19 across the spectrum of HIV.HIV 感染者中 COVID-19 的严重程度。
Curr Opin HIV AIDS. 2023 May 1;18(3):119-125. doi: 10.1097/COH.0000000000000791. Epub 2023 Mar 17.
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Infect Drug Resist. 2022 Dec 2;15:7037-7042. doi: 10.2147/IDR.S390333. eCollection 2022.
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