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国际兽医犬运动障碍工作组 ECVN 共识声明:术语和分类。

International veterinary canine dyskinesia task force ECVN consensus statement: Terminology and classification.

机构信息

MedVet Chicago, Chicago, Illinois, USA.

Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.

出版信息

J Vet Intern Med. 2021 May;35(3):1218-1230. doi: 10.1111/jvim.16108. Epub 2021 Mar 26.

Abstract

Movement disorders are a heterogeneous group of clinical syndromes in humans and animals characterized by involuntary movements without changes in consciousness. Canine movement disorders broadly include tremors, peripheral nerve hyperexcitability disorders, paroxysmal dyskinesia, and dystonia. Of these, canine paroxysmal dyskinesias remain one of the more difficult to identify and characterize in dogs. Canine paroxysmal dyskinesias include an array of movement disorders in which there is a recurrent episode of abnormal, involuntary, movement. In this consensus statement, we recommend standard terminology for describing the various movement disorders with an emphasis on paroxysmal dyskinesia, as well as a preliminary classification and clinical approach to reporting cases. In the clinical approach to movement disorders, we recommend categorizing movements into hyperkinetic vs hypokinetic, paroxysmal vs persistent, exercise-induced vs not related to exercise, using a detailed description of movements using the recommended terminology presented here, differentiating movement disorders vs other differential diagnoses, and then finally, determining whether the paroxysmal dyskinesia is due to either inherited or acquired etiologies. This consensus statement represents a starting point for consistent reporting of clinical descriptions and terminology associated with canine movement disorders, with additional focus on paroxysmal dyskinesia. With consistent reporting and identification of additional genetic mutations responsible for these disorders, our understanding of the phenotype, genotype, and pathophysiology will continue to develop and inform further modification of these recommendations.

摘要

运动障碍是人类和动物中一组异质性的临床综合征,其特征是无意识的不自主运动。犬运动障碍广泛包括震颤、周围神经兴奋性过高疾病、阵发性运动障碍和肌张力障碍。在这些疾病中,犬阵发性运动障碍仍然是在犬中更难以识别和描述的疾病之一。犬阵发性运动障碍包括一系列运动障碍,其中存在反复发作的异常、不自主的运动。在本共识声明中,我们推荐了用于描述各种运动障碍的标准术语,重点是阵发性运动障碍,以及初步的分类和临床报告病例的方法。在运动障碍的临床方法中,我们建议将运动分为过度运动与运动减少、阵发性与持续性、与运动相关与不相关,使用推荐术语详细描述运动,区分运动障碍与其他鉴别诊断,最后确定阵发性运动障碍是由于遗传性还是获得性病因引起的。本共识声明代表了与犬运动障碍相关的临床描述和术语的一致报告的起点,重点是阵发性运动障碍。随着对这些疾病负责的遗传突变的一致报告和识别,我们对表型、基因型和病理生理学的理解将不断发展,并进一步修改这些建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3357/8162615/f7c96c000a93/JVIM-35-1218-g002.jpg

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