Soughi Meryem, Alheyasat Riham, Baybay Hanane, Tahiri Elousrouti Layla, Mernissi FatimaZahra
Department of Dermatology, University Hospital Hassan II, Unités de Recherche Labellisées (URL) Centre National pour la Recherche Scientifique et Technique (CNRST) N15, Fez, MAR.
Human Pathology, Biomedicine and Environment Laboratory, Faculty of Medicine, Pharmacy and Dental Medicine, Sidi Mohamed ben Abdellah University, Fez, MAR.
Cureus. 2025 Mar 26;17(3):e81232. doi: 10.7759/cureus.81232. eCollection 2025 Mar.
Renal cell carcinoma (RCC) is a malignancy that can, in rare cases, present initially with cutaneous metastases, often reflecting an advanced stage. We report the case of a 71-year-old asymptomatic patient who presented with a gradually enlarging, raised lesion on the face over two years, clinically resembling a pyogenic granuloma. An excisional biopsy confirmed the diagnosis of cutaneous metastasis from clear cell RCC. Further staging investigations revealed a mass in the upper pole of the left renal cortex, a suspicious lesion in the lower pole, and bilateral pulmonary nodules, suggesting metastatic spread. The patient was started on sunitinib, resulting in both clinical and radiological improvement.
肾细胞癌（RCC）是一种恶性肿瘤，在极少数情况下，最初可能会出现皮肤转移，这通常反映疾病已处于晚期。我们报告一例71岁无症状患者的病例，该患者面部出现一个逐渐增大的隆起性病变，持续两年，临床上类似化脓性肉芽肿。切除活检确诊为透明细胞肾细胞癌的皮肤转移。进一步的分期检查发现左肾皮质上极有一个肿块，下极有一个可疑病变，以及双侧肺结节，提示有转移扩散。该患者开始使用舒尼替尼治疗，临床和影像学均有改善。
