Shandong Provincial Key Laboratory for Biology of Vegetable Diseases and Insect Pests, College of Plant Protection, Shandong Agricultural University, Tai'an, Shandong 271018, China.
Key Laboratory of Pesticide Toxicology & Application Technique, Shandong Agricultural University, Tai'an, Shandong 271018, China.
Pestic Biochem Physiol. 2021 Mar;173:104784. doi: 10.1016/j.pestbp.2021.104784. Epub 2021 Jan 20.
Mefentrifluconazole is the first product of a new sub-class of triazoles fungicides, i.e., the isopropanol triazoles, with the broad spectrum and high activity. In this study, the potential and biochemical activities of mefentrifluconazole against Botrytis cinerea were investigated. The frequency distribution of all EC values of mefentrifluconazole against mycelial growth and germ tube elongation of 106 isolates formed unimodal curve, with the mean EC values of 0.124 ± 0.025 and 0.015 ± 0.008 μg/mL, respectively. The effect of mefentrifluconazole against gray mold was determined on detached leaves of cucumber in vivo, the treatment of mefentrifluconazole at 200 μg/mL provided 100% preventative efficacy and 72.7% curative efficacy. No evident correlation was detected between the sensitivity of B. cinerea to mefentrifluconazole and that to tebuconazole, difenoconazole, myclobutanil, hexaconazole, triadimefon, flusilazole and pyrisoxazole (P > 0.05). Mefentrifluconazole treatment resulted in the increase of mycelium branch, the decrease of ergosterol content and the changes of the permeability of cell membrane. These studies evaluated the potential of mefentrifluconazole to control gray mold and helped us to understand the possible biochemical activity of mefentrifluconazole against B.cinerea.
氟醚菌酰胺是新型三唑类杀菌剂异丙醇三唑类中的第一个产品，具有广谱和高效的特点。本研究探讨了氟醚菌酰胺对灰葡萄孢的潜在生物化学活性。106 个分离株的菌丝生长和芽管伸长的 EC 值的频率分布呈单峰曲线，平均 EC 值分别为 0.124±0.025 和 0.015±0.008μg/mL。在活体黄瓜离体叶片上测定氟醚菌酰胺对灰霉病的防治效果，氟醚菌酰胺 200μg/mL 处理的预防效果为 100%，治疗效果为 72.7%。灰葡萄孢对氟醚菌酰胺的敏感性与对戊唑醇、烯唑醇、嘧菌酯、己唑醇、三唑酮、氟硅唑和吡唑醚菌酯的敏感性之间无显著相关性（P＞0.05）。氟醚菌酰胺处理导致菌丝分枝增加，麦角固醇含量降低，细胞膜通透性改变。这些研究评估了氟醚菌酰胺控制灰霉病的潜力，有助于我们了解氟醚菌酰胺对灰葡萄孢可能的生物化学活性。
