Department of Radiology, New York-Presbyterian Hospital, and Weill Cornell Medicine, New York, NY, USA.
Department of Cardiology, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea.
Curr Atheroscler Rep. 2021 Mar 26;23(5):21. doi: 10.1007/s11883-021-00924-5.
We aimed to summarize the current evidence regarding the association between breast arterial calcification (BAC) and atherosclerotic cardiovascular disease (ASCVD) in women and discuss the potential role of BAC in the risk stratification and preventive approaches for ASCVD.
BAC has emerged as a potential women-specific risk marker for ASCVD. Although BAC presents as a medial calcification of the arteries, notably different from the intimal atherosclerotic process, current evidence supports a correlation between BAC and ASCVD risk factors or subclinical and clinical ASCVD, such as coronary artery disease or stroke. As millions of women undergo mammograms each year, the potential clinical application of BAC in enhanced ASCVD risk estimation, with no additional cost or radiation, has tremendous appeal. Although further research regarding optimal risk assessment and management in women with BAC is required, the presence of BAC should prompt healthy cardiovascular lifestyle modifications.
本文旨在总结目前关于女性乳腺动脉钙化（BAC）与动脉粥样硬化性心血管疾病（ASCVD）之间的关联的证据，并讨论 BAC 在 ASCVD 风险分层和预防策略中的潜在作用。
BAC 已成为女性 ASCVD 的一个潜在特异性风险标志物。虽然 BAC 表现为动脉的中层钙化，与内膜粥样硬化过程明显不同，但目前的证据支持 BAC 与 ASCVD 危险因素或亚临床和临床 ASCVD（如冠状动脉疾病或中风）之间存在相关性。由于每年有数百万女性接受乳房 X 光检查，因此 BAC 在增强 ASCVD 风险评估中的潜在临床应用具有巨大的吸引力，且不会增加额外的成本或辐射。尽管需要进一步研究 BAC 女性的最佳风险评估和管理，但 BAC 的存在应促使其进行健康的心血管生活方式改变。
