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大肠杆菌对白细胞的固定作用。产肠毒素细菌的研究(作者译)

[Immobilization of leukocytes by Escherichia coli. A study with enterotoxigenic bacteria (author's transl)].

作者信息

Ohgke H

出版信息

Zentralbl Bakteriol Orig A. 1977 Oct;239(2):162-71.

PMID:337733
Abstract

Rabbit peritoneal leukocytes showed reduced random motility and chemotactic responsiveness after incubation in the high molecular weight-fraction of Escherichia coli culture filtrates. Two leukocyte-immobilizing factors appeared in the incubation media. One of these factors was thought to be identical with the migration inhibiting substance described by Udaka. The other immobilizing factor was dialyzable and gave a molecular weight of about 300 by column chromatography. Minimal formation of the factors occurred in the presence of E. coli heat-labile Enterotoxin.

摘要

在大肠杆菌培养滤液的高分子量组分中孵育后,兔腹膜白细胞的随机运动性和趋化反应性降低。孵育培养基中出现了两种白细胞固定因子。其中一种因子被认为与宇田描述的迁移抑制物质相同。另一种固定因子可透析,通过柱色谱法测得分子量约为300。在大肠杆菌不耐热肠毒素存在的情况下,这些因子的形成最少。

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