Ohgke H, Wagner D
Zentralbl Bakteriol Orig A. 1977 Jul;238(3):350-4.
Heat-stable Escherichia coli enterotoxin was assayed by the method of DEAN determining gut weight to body weight ratios in infant mice. The enterotoxic responses were significantly lower than in saline treated controls when Phenylbutazone at 20 mcg/mouse was administered subcutaneously 30 minutes prior to intragastric toxin challenge. The trials were performed with lyophilized culture filtrates of E. coli O 149:K91 (B) K88 ab (L), and three other enterotoxigenic strains one of which was isolated from an outbreak of swine oedema disease, the other two strains originated from the stools of diseased children.
采用迪恩（DEAN）测定幼鼠肠重与体重比的方法对热稳定型大肠杆菌肠毒素进行检测。在胃内毒素攻击前30分钟，以每只小鼠20微克的剂量皮下注射保泰松，其肠毒性反应显著低于生理盐水处理的对照组。试验使用了大肠杆菌O 149:K91（B）K88 ab（L）的冻干培养滤液，以及其他三种产肠毒素菌株，其中一种从猪水肿病暴发中分离得到，另外两种菌株源自患病儿童的粪便。
