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Association between leukocytospermia and semen interleukin-6 and tumor necrosis factor-alpha in infertile men.白细胞精子症与不育男性精液中白细胞介素-6 和肿瘤坏死因子-α 的关系。
Andrology. 2018 Sep;6(5):775-780. doi: 10.1111/andr.12513. Epub 2018 Jul 6.
2
Cadmium effects on sperm morphology and semenogelin with relates to increased ROS in infertile smokers: An in vitro and in silico approach.镉对不育吸烟者精子形态和精液凝胶蛋白的影响及其与活性氧增加的关系:体外和计算机模拟方法
Reprod Biol. 2018 Jun;18(2):189-197. doi: 10.1016/j.repbio.2018.04.003. Epub 2018 May 3.
3
Impact of Subinguinal Varicocelectomy on Serum Testosterone to Estradiol Ratio in Male Patients With Infertility.腹股沟下精索静脉结扎术对男性不育患者血清睾酮与雌二醇比值的影响。
Urology. 2018 Jul;117:70-77. doi: 10.1016/j.urology.2018.03.039. Epub 2018 Apr 6.
4
Sexual dysfunction and male infertility.性功能障碍与男性不育。
Nat Rev Urol. 2018 May;15(5):287-307. doi: 10.1038/nrurol.2018.20. Epub 2018 Mar 13.
5
Routine assessment of sperm DNA fragmentation in clinical practice: commentary and perspective.临床实践中精子DNA片段化的常规评估:评论与展望。
Transl Androl Urol. 2017 Sep;6(Suppl 4):S640-S643. doi: 10.21037/tau.2017.03.29.
6
Causes of male infertility: a 9-year prospective monocentre study on 1737 patients with reduced total sperm counts.男性不育的原因:一项针对1737例精子总数减少患者的9年前瞻性单中心研究。
Hum Reprod. 2017 Jan;32(1):18-31. doi: 10.1093/humrep/dew284. Epub 2016 Nov 17.
7
Varicocele among infertile men in Qatar.卡塔尔不育男性中的精索静脉曲张。
Andrologia. 2017 May;49(4). doi: 10.1111/and.12637. Epub 2016 Jul 12.
8
Genetics of male infertility: from research to clinic.男性不育的遗传学:从研究到临床
Reproduction. 2015 Nov;150(5):R159-74. doi: 10.1530/REP-15-0261.
9
Higher pregnancy rates using testicular sperm in men with severe oligospermia.严重少精子症男性使用睾丸精子可提高妊娠率。
Fertil Steril. 2015 Dec;104(6):1382-7. doi: 10.1016/j.fertnstert.2015.08.008. Epub 2015 Sep 9.
10
The effects of cigarette smoking on male fertility.吸烟对男性生育能力的影响。
Postgrad Med. 2015 Apr;127(3):338-41. doi: 10.1080/00325481.2015.1015928. Epub 2015 Feb 19.

科威特一项基于人群的男性不育症流行病学及危险因素研究。

A population-based study of the epidemiology and the risk factors for male infertility in Kuwait.

作者信息

Al-Kandari Ahmed M, Al-Enezi Ahmad N, Ibrahim Hamdy, Alkandari Omar

机构信息

Department of Surgery (Urology), Faculty of Medicine, Kuwait University, Safat, Kuwait.

Department of Surgery, Urology Unit, Mubarak Al-Kabeer Hospital, Sabah Al-Ahmad Center, Kuwait.

出版信息

Urol Ann. 2020 Oct-Dec;12(4):319-323. doi: 10.4103/UA.UA_50_20. Epub 2020 Aug 10.

DOI:10.4103/UA.UA_50_20
PMID:33776326
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7992523/
Abstract

PURPOSE

Infertility has become one of the foremost public health concerns, affecting a large number of couples. This research aimed to study and analyze the epidemiological data of male infertility including demographic characteristics and potential accountable factors.

MATERIALS AND METHODS

A population-based study was carried out among male patients of one center. Different factors have been investigated such as family history, smoking, and varicocele. Data were analyzed using the STATA statistical software package.

RESULTS

A total of 608 male patients aged between 22 and 56 years were included. Out of them, there were 544 (89.95%) married, 48 (7.9%) married more than once, and 10 (1.6%) divorced. Primary infertility was noted in 478 (78.6%) patients. The most commonly reported sexual disorder was erectile dysfunction 53 (8.7%), while decreased libido was detected in 8 (1.3%) patients. Varicocele was present among 507 (86%) patients. Semen analyses of infertile patients revealed that 43 (8.2%) cases had normal semen tests. In contrast, oligoasthenospermia was the most commonly reported semen abnormality 158 (30.2%). A total of 198 patients underwent assisted reproductive technique.

CONCLUSION

This study concluded that primary infertility is the most common type among all infertile male patients who visited our center. The risk factors of male infertility include positive family history, smoking, and varicocele.

摘要

目的

不孕症已成为最主要的公共卫生问题之一,影响着大量夫妇。本研究旨在研究和分析男性不育的流行病学数据,包括人口统计学特征和潜在的相关因素。

材料与方法

在一个中心的男性患者中开展了一项基于人群的研究。调查了不同因素,如家族史、吸烟和精索静脉曲张。使用STATA统计软件包对数据进行分析。

结果

共纳入608例年龄在22至56岁之间的男性患者。其中,544例(89.95%)已婚,48例(7.9%)再婚,10例(1.6%)离婚。478例(78.6%)患者为原发性不孕。最常报告的性功能障碍是勃起功能障碍53例(8.7%),而8例(1.3%)患者存在性欲减退。507例(86%)患者存在精索静脉曲张。不育患者的精液分析显示,43例(8.2%)精液检查正常。相比之下,少弱精子症是最常报告的精液异常,有158例(30.2%)。共有198例患者接受了辅助生殖技术。

结论

本研究得出结论,原发性不孕是前来我们中心就诊的所有不育男性患者中最常见的类型。男性不育的危险因素包括家族史阳性、吸烟和精索静脉曲张。