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新型扩展焦深老视矫正人工晶状体的临床结果：初步研究。

Clinical Outcomes with a Novel Extended Depth of Focus Presbyopia-Correcting Intraocular Lens: Pilot Study.

作者信息

Iradier María T, Cruz Verónica, Gentile Naty, Cedano Priscila, Piñero David P

机构信息

Iradier Eye Clinic, Madrid, Spain.

Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, Spain.

出版信息

Clin Ophthalmol. 2021 Mar 19;15:1215-1221. doi: 10.2147/OPTH.S297985. eCollection 2021.

DOI:10.2147/OPTH.S297985
PMID:33776418
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7989957/
Abstract

PURPOSE

To evaluate the clinical outcomes of cataract surgery with implantation of a novel model of extended depth of focus (EDOF) intraocular lens (IOL).

METHODS

Pilot case series enrolling a total of 27 eyes of 16 patients (49 to 84 years) undergoing uncomplicated phacoemulsification cataract surgery with implantation of the EDOF IOL Synthesis PLUS (Cutting Edge, Montpellier, France). Near (UNVA, uncorrected near visual acuity; DCNVA, distance-corrected near visual acuity) and distance visual acuity (uncorrected and corrected distance visual acuity, UDVA and CDVA), monocular defocus curve and refractive outcomes were evaluated during a 3-month follow-up.

RESULTS

Mean postoperative UDVA, UNVA and DCNVA were 0.11±0.17, 0.14±0.22 and 0.37±0.36 logMAR, respectively. A total of 84.6%, 91.7%, and 96.3% of eyes achieved postoperative UDVA, UNVA and CDVA of 0.20 logMAR or better. A total of 78.6% of eyes achieved postoperative DCNVA of 0.30 logMAR or better. Mean postoperative spherical equivalent was -0.76±0.53 D. The distance-corrected visual acuity was maintained on average over a value of 0.30 logMAR for the range of defocus levels between +1.00 and -1.50 D.

CONCLUSION

The implantation of the Synthesis plus EDOF IOL after cataract surgery seems to provide functional levels of distance, intermediate and near visual acuity. The near visual performance with this new IOL might be significantly enhanced using a micro-monovision approach. The results of this pilot study should be confirmed in future clinical trials.

摘要

目的

评估植入新型扩展焦深（EDOF）人工晶状体（IOL）的白内障手术的临床效果。

方法

前瞻性病例系列研究，共纳入16例患者（49至84岁）的27只眼，这些患者均接受了植入EDOF人工晶状体Synthesis PLUS（法国蒙彼利埃的Cutting Edge公司生产）的无并发症超声乳化白内障手术。在3个月的随访期间，评估了近视力（未矫正近视力，UNVA；远距矫正近视力，DCNVA）和远视力（未矫正和矫正远视力，UDVA和CDVA）、单眼散焦曲线和屈光结果。

结果

术后平均UDVA、UNVA和DCNVA分别为0.11±0.17、0.14±0.22和0.37±0.36 logMAR。分别有84.6%、91.7%和96.3%的术眼术后UDVA、UNVA和CDVA达到或优于0.20 logMAR。共有78.6%的术眼术后DCNVA达到或优于0.30 logMAR。术后平均球镜等效度为-0.76±0.53 D。在+1.00至-1.50 D的散焦水平范围内，远距矫正视力平均维持在0.30 logMAR以上。

结论

白内障手术后植入Synthesis plus EDOF人工晶状体似乎能提供远、中、近视力的功能性水平。采用微单眼视方法可能会显著提高这种新型人工晶状体的近视力表现。本前瞻性研究的结果应在未来的临床试验中得到证实。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/979a/7989957/c0a34edadcae/OPTH-15-1215-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/979a/7989957/688befcbd03a/OPTH-15-1215-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/979a/7989957/cdd1b08014d1/OPTH-15-1215-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/979a/7989957/c0a34edadcae/OPTH-15-1215-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/979a/7989957/688befcbd03a/OPTH-15-1215-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/979a/7989957/cdd1b08014d1/OPTH-15-1215-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/979a/7989957/c0a34edadcae/OPTH-15-1215-g0003.jpg

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