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动机性访谈对血糖控制不佳的青少年 1 型糖尿病患者的影响:一项随机对照初步试验。

Motivational Interviewing and Glycemic Control in Adolescents With Poorly Controlled Type 1 Diabetes: A Randomized Controlled Pilot Trial.

机构信息

Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Faculty of Social Sciences (Psychology), Tampere University, Tampere, Finland.

出版信息

Front Endocrinol (Lausanne). 2021 Mar 12;12:639507. doi: 10.3389/fendo.2021.639507. eCollection 2021.

Abstract

A multicenter randomized controlled pilot trial investigated whether motivational interviewing (MI) by diabetes physicians improves glycemic control and variability in the context of follow-up for adolescent patients with poorly controlled type 1 diabetes. Patients ( = 47) aged 12 to 15.9 years who showed poor glycemic control (HbA1c >75 mmol/mol/9.0%) were randomized to standard education (SE) only or MI+SE, with study physicians randomized to employ MI+SE ( = 24 patients) or SE only ( = 23). For one year of follow-up, the main outcome measurements were obtained at three-month visits (HbA1c) or six-monthly: time in range (TIR) and glycemic variability (CV). Mean adjusted 12-month change in HbA1c was similar between the MI+SE and SE-only group (-3.6 vs. -1.0 mmol/mol), and no inter-group differences were visible in the mean adjusted 12-month change in TIR (-0.8 vs. 2.6%; = 0.53) or CV (-0.5 vs. -6.2; = 0.26). However, the order of entering the study correlated significantly with the 12-month change in HbA1c in the MI+SE group ( = -0.5; = 0.006) and not in the SE-only group ( = 0.2; = 0.4). No link was evident between MI and changes in quality of life. The authors conclude that MI's short-term use by diabetes physicians managing adolescents with poorly controlled type 1 diabetes was not superior to SE alone; however, improved skills in applying the MI method at the outpatient clinic may produce greater benefits in glycemic control.

摘要

一项多中心随机对照试验研究了糖尿病医生进行的动机性访谈(MI)是否可以改善青少年 1 型糖尿病控制不佳患者的血糖控制和变异性,作为随访的一部分。12 至 15.9 岁血糖控制不佳(HbA1c>75 mmol/mol/9.0%)的患者被随机分为仅接受标准教育(SE)或 MI+SE,研究医生随机采用 MI+SE(n=24)或仅 SE(n=23)。在为期一年的随访中,主要的测量结果在三个月(HbA1c)或六个月时获得:血糖控制达标时间(TIR)和血糖变异性(CV)。MI+SE 组和 SE 组的平均调整后 12 个月 HbA1c 变化相似(-3.6 与-1.0 mmol/mol),TIR(-0.8 与 2.6%; = 0.53)或 CV(-0.5 与-6.2; = 0.26)的平均调整后 12 个月变化无组间差异。然而,进入研究的顺序与 MI+SE 组的 12 个月 HbA1c 变化显著相关( =-0.5; = 0.006),而与 SE 组无关( =0.2; = 0.4)。MI 与生活质量变化之间没有明显联系。作者得出结论,糖尿病医生在管理青少年 1 型糖尿病控制不佳患者时短期使用 MI 并不优于单独的 SE;然而,在门诊中应用 MI 方法的技能提高可能会对血糖控制产生更大的益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffd1/7994365/f2510f4d5d1b/fendo-12-639507-g001.jpg

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