Modeling COVID-19 Pandemic with Hierarchical Quarantine and Time Delay.

COVID-19 comes out as a sudden pandemic disease within human population. The pandemic dynamics of COVID-19 needs to be studied in detail. A pandemic model with hierarchical quarantine and time delay is proposed in this paper. In the COVID-19 case, the virus incubation period and the antibody failure will cause the time delay and reinfection, respectively, and the hierarchical quarantine strategy includes home isolation and quarantine in hospital. These factors that affect the spread of COVID-19 are well considered and analyzed in the model. The stability of the equilibrium and the nonlinear dynamics is studied as well. The threshold value of the bifurcation is deduced and quantitatively analyzed. Numerical simulations are performed to establish the analytical results with suitable examples. The research reveals that the COVID-19 outbreak may recur over a period of time, which can be helpful to increase the number of tested people with or without symptoms in order to be able to early identify the clusters of infection. And before the effective vaccine is successfully developed, the hierarchical quarantine strategy is currently the best way to prevent the spread of this pandemic.