Garrity James A
Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States.
J Neurol Surg B Skull Base. 2021 Feb;82(1):96-99. doi: 10.1055/s-0040-1722636. Epub 2021 Feb 2.
This study was aimed to illustrate the features and complexities of nonspecific orbital inflammation via discussion of two representative cases. Present study is a retrospective case review. The study was conducted at a tertiary care medical center. Two patients with nonspecific orbital inflammation were participants of this retrospective study. Outcome of the study was disease-free patients and off all medications. At follow-up, both patients are disease free and off all medications. Surgery plays a diagnostic and therapeutic role. While the clinical subtype is important for differential diagnosis and symptomatic treatment, the histologic subtype is similarly important. For inflammatory dacryoadenitis, surgery can be therapeutic. For extensive granulomatosis with polyangiitis, debulking surgery may allow better penetration of medications, especially rituximab.
本研究旨在通过讨论两例典型病例来说明非特异性眼眶炎症的特征和复杂性。本研究为回顾性病例分析。研究在一家三级医疗中心进行。两名非特异性眼眶炎症患者参与了这项回顾性研究。研究结果为疾病痊愈且停用所有药物。随访时，两名患者均无疾病且停用了所有药物。手术具有诊断和治疗作用。虽然临床亚型对鉴别诊断和对症治疗很重要，但组织学亚型同样重要。对于炎性泪腺炎，手术具有治疗作用。对于广泛性肉芽肿性多血管炎，减瘤手术可能使药物，尤其是利妥昔单抗，更好地渗透。
