不完全川崎病的正确识别。
Correct identification of incomplete Kawasaki disease.
作者信息
Li Tianhua, Feng Jie, Li Na, Liu Tingting
机构信息
Department of Paediatrics, Weifang People's Hospital, Weifang City, Shandong Province, China.
Department of Ultrasound, Weifang People's Hospital, Weifang City, Shandong Province, China.
出版信息
J Int Med Res. 2021 Mar;49(3):3000605211001712. doi: 10.1177/03000605211001712.
Abstract
Incomplete Kawasaki disease (IKD) is characterized by a longer fever time, younger age of onset, and higher incidence of coronary artery disease compared with complete Kawasaki disease. Kawasaki disease is often difficult to diagnose early because of its incomplete clinical symptoms. This issue could delay treatment and harm the health of the child. This article reviews the clinical characteristics and pathogenesis of IKD to help clinicians understand the symptoms of IKD, make the correct diagnosis, and provide timely treatment.
摘要
不完全川崎病（IKD）的特点是发热时间较长、发病年龄较小，与完全性川崎病相比，冠状动脉疾病的发病率更高。由于川崎病的临床症状不完整，早期往往难以诊断。这个问题可能会延误治疗并损害儿童健康。本文综述了不完全川崎病的临床特征和发病机制，以帮助临床医生了解不完全川崎病的症状，做出正确诊断，并提供及时治疗。
相似文献
1
Correct identification of incomplete Kawasaki disease.不完全川崎病的正确识别。
J Int Med Res. 2021 Mar;49(3):3000605211001712. doi: 10.1177/03000605211001712.
2
[Diagnosis and treatment of incomplete Kawasaki disease in children].[儿童不完全川崎病的诊断与治疗]
Zhongguo Dang Dai Er Ke Za Zhi. 2023 Mar 15;25(3):238-243. doi: 10.7499/j.issn.1008-8830.2209127.
3
Treatment change and coronary artery abnormality in incomplete Kawasaki disease.不完全川崎病的治疗改变与冠状动脉异常。
Pediatr Int. 2020 Jul;62(7):779-784. doi: 10.1111/ped.14242.
4
Clinical manifestations and risk factors of coronary artery lesions in children with Kawasaki disease.川崎病患儿冠状动脉病变的临床表现及危险因素。
Medicine (Baltimore). 2023 Sep 15;102(37):e34939. doi: 10.1097/MD.0000000000034939.
5
[Clinical features of children with incomplete Kawasaki disease].[不完全川崎病患儿的临床特征]
Zhongguo Dang Dai Er Ke Za Zhi. 2016 Nov;18(11):1111-1114. doi: 10.7499/j.issn.1008-8830.2016.11.011.
6
Two cases of Kawasaki disease: Clinical characteristics and onset of fever and gastrointestinal symptoms.两例川崎病：临床特征和发热及胃肠道症状的发病情况。
Immun Inflamm Dis. 2023 Jul;11(7):e929. doi: 10.1002/iid3.929.
7
Prevalence of coronary artery abnormality in incomplete Kawasaki disease.不完全川崎病中冠状动脉异常的患病率
Pediatr Int. 2007 Aug;49(4):421-6. doi: 10.1111/j.1442-200X.2007.02396.x.
8
Anterior uveitis as an early diagnostic marker in incomplete Kawasaki disease.前葡萄膜炎作为不完全川崎病的早期诊断标志物。
BMC Pediatr. 2024 Oct 10;24(1):644. doi: 10.1186/s12887-024-05133-y.
9
Risk of coronary artery lesions in young infants with Kawasaki disease: need for a new diagnostic method.川崎病幼儿冠状动脉病变的风险：对新诊断方法的需求。
Int J Rheum Dis. 2018 Mar;21(3):746-754. doi: 10.1111/1756-185X.13223. Epub 2017 Nov 3.
10
Case of Incomplete Kawasaki Disease with No Symptoms Except Fever Causing the Development of Coronary Aneurysm.除发热外无其他症状的不完全川崎病导致冠状动脉瘤形成的病例。
Int Heart J. 2019 Jul 27;60(4):1006-1008. doi: 10.1536/ihj.18-647. Epub 2019 Jun 14.
引用本文的文献
1
Kawasaki Disease Presenting Uncommonly with Torticollis: A Case Report.以斜颈为罕见表现的川崎病：一例报告
Clin Case Rep. 2025 Aug 22;13(9):e70796. doi: 10.1002/ccr3.70796. eCollection 2025 Sep.
2
Incomplete Kawasaki disease presenting primarily with cough: a case report and brief literature review.主要以咳嗽为表现的不完全川崎病：一例报告及文献简要综述
BMC Pediatr. 2025 Aug 20;25(1):632. doi: 10.1186/s12887-025-05957-2.
3
Endovascular Management of Upper Limb Arterial Aneurysms in a Child With Kawasaki Disease.川崎病患儿上肢动脉瘤的血管内治疗
EJVES Vasc Forum. 2025 Apr 19;64:16-19. doi: 10.1016/j.ejvsvf.2025.04.005. eCollection 2025.
4
Integrative machine learning identifies robust inflammation-related diagnostic biomarkers and stratifies immune-heterogeneous subtypes in Kawasaki disease.整合机器学习可识别川崎病中与炎症相关的可靠诊断生物标志物，并对免疫异质性亚型进行分层。
Pediatr Rheumatol Online J. 2025 Jun 2;23(1):61. doi: 10.1186/s12969-025-01114-2.
5
Advancing multidisciplinary management of pediatric hyperinflammatory disorders.推进儿童高炎症性疾病的多学科管理。
Front Pediatr. 2025 Apr 30;13:1553861. doi: 10.3389/fped.2025.1553861. eCollection 2025.
6
Missed or Delayed Diagnosis of Heart Disease by the General Pediatrician.普通儿科医生对心脏病的漏诊或误诊。
Children (Basel). 2025 Mar 15;12(3):366. doi: 10.3390/children12030366.
7
[Berberine ameliorates coronary artery endothelial cell injury in Kawasaki disease through complement and coagulation cascades].[黄连素通过补体和凝血级联反应改善川崎病冠状动脉内皮细胞损伤]
Zhongguo Dang Dai Er Ke Za Zhi. 2025 Jan 15;27(1):101-108. doi: 10.7499/j.issn.1008-8830.2406075.
8
Cardiac Arrest During Exertion as a Presentation of Undiagnosed Kawasaki Disease: A Case Report.运动时心脏骤停作为未确诊川崎病的一种表现：一例报告
J Clin Med. 2024 Oct 24;13(21):6380. doi: 10.3390/jcm13216380.
9
Metagenomic analysis demonstrates distinct changes in the gut microbiome of Kawasaki diseases children.宏基因组分析表明川崎病患儿肠道微生物组有明显变化。
Front Immunol. 2024 Jul 22;15:1416185. doi: 10.3389/fimmu.2024.1416185. eCollection 2024.
10
Guideline for the diagnosis and treatment of incomplete Kawasaki disease in children in China.中国儿童不完全川崎病诊断与治疗指南。
BMC Pediatr. 2024 Jul 26;24(1):477. doi: 10.1186/s12887-024-04961-2.
本文引用的文献
1
The Risk Prediction of Coronary Artery Lesions through the Novel Hematological Z-Values in 4 Chronological Age Subgroups of Kawasaki Disease.通过新型血液学Z值对川崎病4个年龄亚组冠状动脉病变的风险预测
Medicina (Kaunas). 2020 Sep 11;56(9):466. doi: 10.3390/medicina56090466.
2
Presentation and Outcomes of Kawasaki Disease in Latin American Infants Younger Than 6 Months of Age: A Multinational Multicenter Study of the REKAMLATINA Network.拉丁美洲6个月以下婴儿川崎病的临床表现及转归：REKAMLATINA网络的多国多中心研究
Front Pediatr. 2020 Jul 16;8:384. doi: 10.3389/fped.2020.00384. eCollection 2020.
3
Kawasaki Disease as the Immune-Mediated Echo of a Viral Infection.川崎病作为病毒感染的免疫介导回声。
Mediterr J Hematol Infect Dis. 2020 Jul 1;12(1):e2020039. doi: 10.4084/MJHID.2020.039. eCollection 2020.
4
Risk factors of intravenous immunoglobulin resistance and coronary arterial lesions in Turkish children with Kawasaki disease.土耳其川崎病患儿静脉注射免疫球蛋白抵抗和冠状动脉病变的危险因素。
Turk J Pediatr. 2020;62(1):1-9. doi: 10.24953/turkjped.2020.01.001.
5
Changes in and significance of platelet function and parameters in Kawasaki disease.川崎病血小板功能及参数变化及意义。
Sci Rep. 2019 Nov 27;9(1):17641. doi: 10.1038/s41598-019-54113-1.
6
Epidemiologic Features of Kawasaki Disease in Shanghai From 2013 Through 2017.2013 年至 2017 年上海川崎病的流行病学特征。
J Epidemiol. 2020 Oct 5;30(10):429-435. doi: 10.2188/jea.JE20190065. Epub 2019 Sep 21.
7
Kawasaki disease in infants less than one year of age: an Italian cohort from a single center.一岁以下婴儿川崎病：单中心意大利队列研究。
BMC Pediatr. 2019 Sep 7;19(1):321. doi: 10.1186/s12887-019-1695-0.
8
Coronary artery lesion risk and mediating mechanism in children with complete and incomplete Kawasaki disease.川崎病完全和不完全患儿冠状动脉损伤风险及中介机制。
J Investig Med. 2019 Aug;67(6):950-956. doi: 10.1136/jim-2018-000898. Epub 2019 Feb 25.
9
Nationwide epidemiologic survey of Kawasaki disease in Japan, 2015-2016.2015 - 2016年日本川崎病全国流行病学调查
Pediatr Int. 2019 Apr;61(4):397-403. doi: 10.1111/ped.13809. Epub 2019 Apr 16.
10
Interleukin-6 is prone to be a candidate biomarker for predicting incomplete and IVIG nonresponsive Kawasaki disease rather than coronary artery aneurysm.白细胞介素-6 易于成为预测川崎病不完全反应和免疫球蛋白静脉注射无反应的候选生物标志物，而非冠状动脉瘤。
Clin Exp Med. 2019 May;19(2):173-181. doi: 10.1007/s10238-018-00544-5. Epub 2019 Jan 8.
Zotero 插件