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[儿童不完全川崎病的诊断与治疗]

[Diagnosis and treatment of incomplete Kawasaki disease in children].

作者信息

Jiao Fu-Yong, Mu Zhi-Long, DU Zhong-Dong, Yang Xiao-Dong, Shen Jie, Xiang Wei, Wang Hong

机构信息

Shaanxi Provincial Kawasaki Disease Treatment Center/Children's Hospital of Shaanxi Provincial People's Hospital, Xi'an 710068, China.

出版信息

Zhongguo Dang Dai Er Ke Za Zhi. 2023 Mar 15;25(3):238-243. doi: 10.7499/j.issn.1008-8830.2209127.

Abstract

Kawasaki disease (KD) is a febrile disease mainly observed in children aged <5 years, with medium- and small-vessel vasculitis as the main lesion. Although KD has been reported for more than 50 years and great progress has been made in the etiology and pathology of KD in recent years, there is still a lack of specific indicators for the early diagnosis of KD, especially with more difficulties in the diagnosis of incomplete Kawasaki disease (IKD). At present, there are no clear diagnostic criteria for IKD, which leads to the failure of the timely identification and standardized treatment of IKD in clinical practice and even induce the development of coronary artery lesion. This article reviews the concept, epidemiological features, diagnosis, treatment, and follow-up management of IKD, in order to deepen the understanding of IKD among clinical workers and help to improve the clinical diagnosis and treatment of KD in China.

摘要

川崎病(KD)是一种主要发生于5岁以下儿童的发热性疾病,以中小血管血管炎为主要病变。尽管KD已被报道50多年,近年来KD的病因和病理学取得了很大进展,但仍缺乏KD早期诊断的特异性指标,尤其是不完全川崎病(IKD)的诊断更加困难。目前,IKD尚无明确的诊断标准,这导致临床实践中IKD不能及时识别和规范治疗,甚至诱发冠状动脉病变。本文综述了IKD的概念、流行病学特征、诊断、治疗及随访管理,以加深临床工作者对IKD的认识,有助于提高我国KD的临床诊治水平。

相似文献

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[Diagnosis and treatment of incomplete Kawasaki disease in children].[儿童不完全川崎病的诊断与治疗]
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本文引用的文献

1
[Pediatric expert consensus on the application of aspirin in Kawasaki disease].[川崎病应用阿司匹林的儿科专家共识]
Zhongguo Dang Dai Er Ke Za Zhi. 2022 Jun 15;24(6):597-603. doi: 10.7499/j.issn.1008-8830.2203190.
2
[The expert consensus on diagnosis and acute-phase treatment of Kawasaki disease].[川崎病诊断与急性期治疗专家共识]
Zhonghua Er Ke Za Zhi. 2022 Jan 2;60(1):6-13. doi: 10.3760/cma.j.cn112140-20211018-00879.
3
[Challenges in the diagnosis and treatment of Kawasaki disease].[川崎病诊断与治疗中的挑战]
Zhonghua Er Ke Za Zhi. 2022 Jan 2;60(1):3-5. doi: 10.3760/cma.j.cn112140-20211104-00927.
4
Shaanxi Provincial Diagnosis and Treatment Center of Kawasaki Disease.陕西省川崎病诊疗中心。
Zhongguo Dang Dai Er Ke Za Zhi. 2021;23(9):867-876. doi: 10.7499/j.issn.1008-8830.2107110.
9
Correct identification of incomplete Kawasaki disease.不完全川崎病的正确识别。
J Int Med Res. 2021 Mar;49(3):3000605211001712. doi: 10.1177/03000605211001712.

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