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日本过去十年间猪对A型流感病毒的抗体反应。

Antibody responses of swine to type A influenza viruses during the past ten years in Japan.

作者信息

Goto H, Ogawa Y, Hirano T, Miwa Y, Piao F Z, Takai M, Noro S, Sakurada N

机构信息

Department of Veterinary Microbiology, Obihiro University of Agriculture and Veterinary Medicine, Japan.

出版信息

Epidemiol Infect. 1988 Jun;100(3):523-6. doi: 10.1017/s095026880006725x.

Abstract

A total of 6346 swine sera collected at an abattoir in the city of Obihiro, Hokkaido during the years 1978-87 were tested for the presence of antibodies to swine and human influenza viruses. A high incidence of antibody to A/New Jersey/8/76 (swine type H1N1) virus was observed throughout the 10 years except for the occasional month and a single long period of 15 months. Antibodies to human H3N2 virus in swine appeared to be related to the epidemics of human influenza which occurred in the study area during the years 1980-3, but unrelated to the epidemics during the years 1984-7. A large number of swine were found to be antibody positive to a human H1N1 virus during the period April to June 1964, and a smaller number, during the period November 1986 to June 1987. Both were in relation to human influenza epidemics. However, there were long periods where human H1N1 antibodies in swine could not be found.

摘要

1978年至1987年期间,在北海道带广市的一家屠宰场收集了6346份猪血清,检测其中是否存在针对猪流感病毒和人流感病毒的抗体。除了偶尔的月份以及长达15个月的单一时间段外,在这10年期间均观察到针对A/新泽西/8/76(猪H1N1型)病毒的高抗体发生率。猪体内针对人H3N2病毒的抗体似乎与1980年至1983年期间研究区域内发生的人流感疫情有关,但与1984年至1987年期间的疫情无关。在1964年4月至6月期间,发现大量猪对人H1N1病毒抗体呈阳性,在1986年11月至1987年6月期间,阳性猪数量较少。这两个时期均与人流感疫情有关。然而,在很长一段时间内都未在猪体内发现人H1N1抗体。

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