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埃塞俄比亚哈瓦萨市哈瓦萨综合专科医院腹泻成年患者的抗菌药物敏感性谱。 (注:原文中“and and”表述有误,可能影响准确理解,但按要求直接翻译)

and and antimicrobial susceptibility profiles among adult patients with complaints of diarrhea at Hawassa comprehensive specialized hospital, Hawassa, Ethiopia.

作者信息

Abera Kassahun, Anticho Tariku Lambiyo, Ali Musa Mohammed

机构信息

Hawassa College of Health Science, Hawassa, Ethiopia.

School of Medical Laboratory Science, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.

出版信息

SAGE Open Med. 2021 Mar 10;9:20503121211000911. doi: 10.1177/20503121211000911. eCollection 2021.

Abstract

INTRODUCTION

Diarrhea is one of the public health important diseases in developing countries. Among the causative agents of diarrhea, serovars and species continue to play a major role in resource-limited countries. The aim of this study was to assess the prevalence of and , risk factors, and antimicrobial susceptibility profiles among adult patients with complaints of diarrhea.

METHODS

A hospital-based cross-sectional study was conducted among adult patients with complaints of diarrhea at Hawassa University Comprehensive Specialized Hospital from March 2019 to November 2019. A structured questionnaire was used to collect sociodemographic, behavioral, and environmental characteristics of participants. Fecal samples were inoculated onto Selenite F broth and Xylose Lysine Dextrose media to isolate serovars and species. Antibiotic susceptibility testing was performed by the Kirby-Bauer method. Data were analyzed by SPSS computer software version 20. Bivariate and multivariable analysis was used to determine the association between dependent and independent variables.

RESULTS

The overall prevalence of serovars and species was 8.6% with 95% confidence interval (3.2-13.8). Participant those who do not wash their hands were three times more likely to be infected with and ( < 0.001) than their counterparts. Participants who consume uncooked food had about two times the chance to be infected with and ( < 0.001) than their counterparts. All serovars of and serotypes of were resistant to ampicillin.

CONCLUSION

In this study, relatively a high prevalence of serovars and species was found among adult patients with complaints of diarrhea at Hawassa University Comprehensive Specialized Hospital. Consuming uncooked food and not washing hands were significantly associated with the prevalence of and .

摘要

引言

腹泻是发展中国家重要的公共卫生疾病之一。在腹泻的致病因素中,血清型和菌种在资源有限的国家继续发挥着主要作用。本研究的目的是评估有腹泻症状的成年患者中[具体病原体名称]的流行情况、危险因素及抗菌药物敏感性谱。

方法

2019年3月至2019年11月,在哈瓦萨大学综合专科医院对有腹泻症状的成年患者进行了一项基于医院的横断面研究。使用结构化问卷收集参与者的社会人口统计学、行为和环境特征。将粪便样本接种到亚硒酸盐F肉汤和木糖赖氨酸脱氧葡萄糖培养基上,以分离[具体病原体名称]血清型和菌种。采用 Kirby-Bauer 法进行抗生素敏感性试验。数据通过SPSS 20.0计算机软件进行分析。采用双变量和多变量分析来确定因变量和自变量之间的关联。

结果

[具体病原体名称]血清型和菌种的总体患病率为8.6%,95%置信区间为(3.2 - 13.8)。不洗手的参与者感染[具体病原体名称]的可能性是洗手者的三倍( P < 0.001)。食用未煮熟食物的参与者感染[具体病原体名称]的可能性是未食用者的两倍左右( P < 0.001)。[具体病原体名称]的所有血清型和[另一具体病原体名称]的所有血清型均对氨苄西林耐药。

结论

在本研究中,哈瓦萨大学综合专科医院有腹泻症状的成年患者中,[具体病原体名称]血清型和菌种的患病率相对较高。食用未煮熟食物和不洗手与[具体病原体名称]的患病率显著相关。

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