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交叉学科推进化学发展:多酸在生物学中的应用。

Interweaving Disciplines to Advance Chemistry: Applying Polyoxometalates in Biology.

机构信息

Universität Wien, Fakultät für Chemie, Institut für Biophysikalische Chemie, Althanstraße 14, Wien 1090, Austria.

出版信息

Inorg Chem. 2021 May 3;60(9):6109-6114. doi: 10.1021/acs.inorgchem.1c00125. Epub 2021 Mar 31.

Abstract

This Viewpoint brings awareness of the challenges and subsequent breakthroughs at the intersection of different disciplines, illustrated by the example of the influence biological entities exerted on a huge class of inorganic coordination compounds, called polyoxometalates (POMs). We highlight the possible effects of biological systems on POMs that need to be considered, thereby emphasizing the depth and complexity of interdisciplinary work. We map POMs' structural, electrochemical, and stability properties in the presence of biomolecules and stress the potential challenges related to inorganic coordination chemistry carried out in biological systems. This Viewpoint shows that new chemistry is available at the intersections between disciplines and aims to guide the community toward a discussion about current as well as future trends in truly interdisciplinary work.

摘要

本文观点提请人们注意不同学科交叉点上的挑战和随后的突破,以生物实体对一类称为多金属氧酸盐(POMs)的巨大无机配位化合物的影响为例。我们强调了需要考虑生物系统对 POMs 可能产生的影响,从而强调了跨学科工作的深度和复杂性。我们绘制了生物分子存在时 POMs 的结构、电化学和稳定性特性,并强调了在生物系统中进行无机配位化学相关的潜在挑战。本观点表明,新的化学可以在学科交叉点上出现,并旨在引导科学界就真正的跨学科工作的当前和未来趋势展开讨论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/125a/8154434/935cb620ffa2/ic1c00125_0003.jpg

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