Department of Health Administration, School of Medicine and Health Management, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Department of Business Administration, School of Economics and Management, Wuchang Institute of Technology, Wuhan, China.
Hum Vaccin Immunother. 2021 Aug 3;17(8):2736-2747. doi: 10.1080/21645515.2021.1899731. Epub 2021 Mar 31.
: To evaluate the awareness of College Students (CSs) of HPV vaccine in China and provide evidence-based recommendations for HPV vaccine's publicity and promotion. Web of Science, PubMed, Science of Direct, EBSCO, China National Knowledge Infrastructure and Wanfang Data were searched. A random effects meta-analysis was conducted to determine pooled estimates of Awareness Rate (AR) for HPV vaccine. Of the 36 studies included, the estimated AR of HPV vaccine was 40.27% (95% : 30.86%, 50.06%) among Chinese CSs. The AR of HPV vaccine was stratified by factors as gender, major, area, city, survey time, and sampling method of the study. The pooled AR of HPV vaccine among CSs was as follows: 44.17% (95% : 31.65%, 57.09%) and 31.93% (95% : 13.25%, 54.30%) for females and males; 44.47% (95% : 29.90%, 59.55%) and 12.02% (95% : 7.69%, 17.15%) for medical-related and nonmedical majors; 44.47% (95% : 28.71-60.82%) and 41.16% (95% : 26.48-56.64%) for Eastern and Midwestern region; 48.86% (95% : 30.63-67.25%) and 33.19% (95% : 22.27-45.12%) for first-tier and second- and third-tier city; 29.67 (95% : 11.44-52.16%) and 38.81 (95% : 27.14-51.21%) for AR before and after HPV vaccine entered in China; 51.51% (95% : 32.21%, 70.53%) and 26.21% (95% : 17.41%, 36.10%) for nonrandom and random sampling. This review indicates that awareness of HPV vaccine among CSs remains relatively low in China compared with European countries. Our findings may provide useful information to better understand the HPV vaccine awareness status among Chinese CSs.
为评估中国大学生对 HPV 疫苗的认知情况，为 HPV 疫苗的宣传和推广提供循证建议。检索了 Web of Science、PubMed、Science Direct、EBSCO、中国知网和万方数据。采用随机效应荟萃分析确定 HPV 疫苗知晓率（AR）的汇总估计值。在纳入的 36 项研究中，中国大学生 HPV 疫苗的估计 AR 为 40.27%（95%：30.86%，50.06%）。HPV 疫苗知晓率按性别、专业、地区、城市、调查时间和研究抽样方法进行分层。大学生 HPV 疫苗的 AR 如下：女性为 44.17%（95%：31.65%，57.09%），男性为 31.93%（95%：13.25%，54.30%）；医学相关专业为 44.47%（95%：29.90%，59.55%），非医学相关专业为 12.02%（95%：7.69%，17.15%）；东部和中西部地区为 44.47%（95%：28.71-60.82%）和 41.16%（95%：26.48-56.64%）；一线城市为 48.86%（95%：30.63-67.25%），二线和三线城市为 33.19%（95%：22.27-45.12%）；HPV 疫苗在中国上市前为 29.67%（95%：11.44-52.16%），上市后为 38.81%（95%：27.14-51.21%）；非随机抽样为 51.51%（95%：32.21%，70.53%），随机抽样为 26.21%（95%：17.41%，36.10%）。本综述表明，与欧洲国家相比，中国大学生对 HPV 疫苗的认知度仍然较低。我们的研究结果可能为更好地了解中国大学生 HPV 疫苗的认知状况提供有用信息。
