National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
School of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Matern Child Health J. 2024 Apr;28(4):746-757. doi: 10.1007/s10995-023-03888-x. Epub 2024 Feb 9.
Human papillomavirus (HPV) vaccination is a promising step toward cervical cancer elimination. This study was conducted to investigate the knowledge, attitude, and HPV vaccine uptake among female adults in mainland China based on a large e-commerce platform.
We conducted a cross-sectional online survey of female adults between March 4 to April 20, 2022. The survey consisted of sociodemographic information, related knowledge, vaccination uptake, and attitudes toward vaccination. We included women aged 18-45 years in the final analysis. Logistic regressions were conducted to explore influencing factors associated with related knowledge, HPV vaccination uptake, and willingness to be vaccinated.
In total, 3,572 female adults (34 years, IQR 30-39) were included in the analysis. The majority of the participants were highly educated (78.7%) with a high monthly family income (79.0%). The median HPV knowledge score was 8.25 out of 11. More than 75% of respondents were unvaccinated, while 95.8% of unvaccinated female adults are willing to be vaccinated. Variables such as age, insurance, vaccination history, and whether one had heard of the HPV vaccine influence HPV vaccination practice (all p-values < 0.05). The main barriers to vaccination were vaccine inaccessibility and the high cost of the vaccine.
The findings of our study highlight a moderate knowledge level, poor vaccination rate, and strong willingness to be vaccinated among Chinese female adults who were better educated and wealthier. Targeted health education and practical support should be provided in the future, to reduce gaps between vaccine uptake and vaccine acceptance.
人乳头瘤病毒（HPV）疫苗接种是消除宫颈癌的有希望的步骤。本研究旨在基于一个大型电子商务平台，调查中国女性成年人对 HPV 疫苗的认知、态度和接种情况。
我们于 2022 年 3 月 4 日至 4 月 20 日期间对女性成年人进行了一项横断面在线调查。调查内容包括社会人口统计学信息、相关知识、疫苗接种情况以及对疫苗接种的态度。我们将 18-45 岁的女性纳入最终分析。采用逻辑回归分析方法探索与相关知识、HPV 疫苗接种率以及接种意愿相关的影响因素。
共纳入 3572 名女性成年人（34 岁，IQR 30-39）进行分析。大多数参与者受教育程度较高（78.7%），家庭月收入较高（79.0%）。HPV 知识得分为 11 分中的 8.25 分，中位数。超过 75%的受访者未接种疫苗，而 95.8%的未接种疫苗的女性成年人表示愿意接种。年龄、保险、接种史以及是否听说过 HPV 疫苗等变量均会影响 HPV 疫苗接种行为（均 P 值<0.05）。疫苗可及性差和疫苗费用高是接种的主要障碍。
本研究结果表明，中国女性成年人具有较高的受教育程度和财富水平，他们对 HPV 疫苗的认知水平中等，疫苗接种率低，但接种意愿较强。未来应提供有针对性的健康教育和实际支持，以缩小疫苗接种率和疫苗接种接受率之间的差距。
